SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ffy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3ffy PUTATIVE
TETRAPYRROLE
(CORRIN/PORPHYRIN)
METHYLASE
(Bacteroides
fragilis) 		4 / 6 LEU A 168
PHE A 171
ALA A 172
LEU A 202
 None
 0.90A 1ukbA-3ffyA:
undetectable		 1ukbA-3ffyA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ffy PUTATIVE
TETRAPYRROLE
(CORRIN/PORPHYRIN)
METHYLASE
(Bacteroides
fragilis) 		3 / 3 GLU A 178
GLU A 201
LEU A 168
 None
 0.74A 1v8bA-3ffyA:
undetectable		 1v8bA-3ffyA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3ffy PUTATIVE
TETRAPYRROLE
(CORRIN/PORPHYRIN)
METHYLASE
(Bacteroides
fragilis) 		5 / 10 ILE A 217
THR A 194
GLN A 170
PHE A 171
LEU A 202
 None
 1.30A 5fhzC-3ffyA:
undetectable		 5fhzC-3ffyA:
11.66