SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 11 ASN P  33
GLU P  73
ALA P   9
GLY P   8
ARG P  28
None
None
None
FAD  P 449 (-3.3A)
None
1.38A 1l5rA-3fg2P:
2.4
1l5rA-3fg2P:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 6 TYR P 317
GLU P 286
ILE P 331
GLY P 377
None
1.12A 1maaB-3fg2P:
undetectable
1maaD-3fg2P:
undetectable
1maaB-3fg2P:
23.83
1maaD-3fg2P:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 9 ILE P  32
ILE P  75
ALA P  30
GLU P  73
ARG P  28
FAD  P 449 ( 4.5A)
None
None
None
None
1.00A 1mrgA-3fg2P:
undetectable
1mrgA-3fg2P:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
3 / 3 ALA P 174
GLY P 151
SER P 187
None
0.57A 2ivuA-3fg2P:
undetectable
2ivuA-3fg2P:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 THR P  95
LEU P  89
ILE P  32
ALA P   7
THR P 106
None
None
FAD  P 449 ( 4.5A)
FAD  P 449 ( 4.7A)
FAD  P 449 (-4.1A)
1.16A 3a50A-3fg2P:
undetectable
3a50A-3fg2P:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 ILE P 273
ALA P  12
ALA P  17
VAL P 259
ILE P 257
None
FAD  P 449 (-3.1A)
None
None
None
0.99A 3e00A-3fg2P:
undetectable
3e00A-3fg2P:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 GLY P   8
LEU P  20
VAL P 303
ILE P 273
LEU P  74
FAD  P 449 (-3.3A)
None
None
None
None
1.18A 3g9eA-3fg2P:
undetectable
3g9eA-3fg2P:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 GLY P   8
VAL P 259
GLY P 274
ARG P  42
ILE P 273
FAD  P 449 (-3.3A)
None
FAD  P 449 (-3.5A)
FAD  P 449 (-3.7A)
None
1.16A 3k13B-3fg2P:
undetectable
3k13B-3fg2P:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 GLY P   8
VAL P 259
GLY P 274
ARG P  42
ILE P 273
FAD  P 449 (-3.3A)
None
FAD  P 449 (-3.5A)
FAD  P 449 (-3.7A)
None
1.16A 3k13C-3fg2P:
undetectable
3k13C-3fg2P:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 7 GLU P 390
VAL P 387
VAL P 342
ALA P 393
None
0.99A 3kp6B-3fg2P:
undetectable
3kp6B-3fg2P:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 TYR P  25
HIS P 101
ILE P  29
LEU P  31
LEU P 104
None
1.32A 3lcvB-3fg2P:
2.4
3lcvB-3fg2P:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 GLY P 274
VAL P 290
ASN P 295
ALA P 255
LEU P 104
FAD  P 449 (-3.5A)
None
None
None
None
1.11A 3mteA-3fg2P:
3.4
3mteA-3fg2P:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
3 / 3 SER P 187
SER P 188
HIS P 194
None
0.72A 3mzeA-3fg2P:
undetectable
3mzeA-3fg2P:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
6 / 12 GLY P 196
ALA P 197
VAL P 168
GLY P 325
VAL P 170
ILE P 199
None
None
None
GOL  P 500 (-3.3A)
None
None
1.39A 3nu5A-3fg2P:
undetectable
3nu5A-3fg2P:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 ILE P 245
ALA P 248
ALA P 249
ILE P  32
LEU P 104
None
None
None
FAD  P 449 ( 4.5A)
None
0.98A 3oapA-3fg2P:
undetectable
3oapA-3fg2P:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 10 ILE P  32
ILE P  75
ALA P  30
GLU P  73
ARG P  28
FAD  P 449 ( 4.5A)
None
None
None
None
0.89A 3u6tA-3fg2P:
undetectable
3u6tA-3fg2P:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 6 THR P 160
ARG P 193
ILE P 199
LEU P 166
GOL  P 500 (-4.4A)
None
None
None
1.09A 4ac9C-3fg2P:
3.2
4ac9C-3fg2P:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 7 LEU P 102
THR P 106
ALA P   7
LEU P   5
None
FAD  P 449 (-4.1A)
FAD  P 449 ( 4.7A)
None
0.97A 4d7bA-3fg2P:
undetectable
4d7bA-3fg2P:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 9 VAL P 147
VAL P 146
GLU P 167
ILE P 199
ALA P 150
None
1.12A 4fwdA-3fg2P:
undetectable
4fwdA-3fg2P:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 8 LEU P 102
THR P 106
ALA P   7
LEU P   5
None
FAD  P 449 (-4.1A)
FAD  P 449 ( 4.7A)
None
0.86A 4iizB-3fg2P:
undetectable
4iizB-3fg2P:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 8 LEU P 102
THR P 106
ALA P   7
LEU P   5
None
FAD  P 449 (-4.1A)
FAD  P 449 ( 4.7A)
None
0.92A 4ik6B-3fg2P:
undetectable
4ik6B-3fg2P:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 ILE P 245
ALA P 248
ALA P 249
ILE P  32
LEU P 104
None
None
None
FAD  P 449 ( 4.5A)
None
1.03A 4nqaH-3fg2P:
undetectable
4nqaH-3fg2P:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4J_A_LNRA412_1
(ENDOTHIAPEPSIN)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 9 ASP P 384
TYR P 317
ASP P 315
SER P 281
PHE P 284
None
1.35A 4y4jA-3fg2P:
undetectable
4y4jA-3fg2P:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 9 ILE P  32
ILE P  75
ALA P  30
GLU P  73
ARG P  28
FAD  P 449 ( 4.5A)
None
None
None
None
0.95A 4yp2B-3fg2P:
undetectable
4yp2B-3fg2P:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 8 HIS P  37
SER P  58
SER P  52
ASP P 130
None
1.21A 5a1iA-3fg2P:
undetectable
5a1iA-3fg2P:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 9 ILE P  32
ILE P  75
ALA P  30
GLU P  73
ARG P  28
FAD  P 449 ( 4.5A)
None
None
None
None
0.96A 5cf9B-3fg2P:
undetectable
5cf9B-3fg2P:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 GLY P   8
LEU P 104
ASN P  33
ARG P  28
LEU P  89
FAD  P 449 (-3.3A)
None
None
None
None
1.41A 5emlA-3fg2P:
3.5
5emlA-3fg2P:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 9 GLN P  41
GLY P  10
GLU P  35
ASN P  33
ALA P  17
None
FAD  P 449 (-3.4A)
FAD  P 449 (-3.4A)
None
None
1.41A 5entC-3fg2P:
undetectable
5entC-3fg2P:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 8 ILE P   6
MET P  79
ILE P 257
LEU P  20
None
FAD  P 449 (-4.5A)
None
None
0.90A 5ieoA-3fg2P:
undetectable
5ieoA-3fg2P:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 6 TYR P 203
ASP P 192
HIS P 191
ILE P 186
None
0.88A 5ih0A-3fg2P:
undetectable
5ih0A-3fg2P:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
6 / 12 ALA P 304
ILE P   6
GLY P  13
THR P 297
LEU P 307
LEU P  31
None
1.39A 5nfjA-3fg2P:
4.0
5nfjA-3fg2P:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 VAL P 134
ALA P 163
LEU P  45
LEU P 126
VAL P 234
None
None
FAD  P 449 ( 4.3A)
None
None
1.18A 5tudA-3fg2P:
undetectable
5tudA-3fg2P:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 ILE P 245
ALA P 248
ALA P 249
ILE P  32
LEU P 104
None
None
None
FAD  P 449 ( 4.5A)
None
0.96A 6a5zD-3fg2P:
undetectable
6a5zD-3fg2P:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 ILE P 245
ALA P 248
ALA P 249
ILE P  32
LEU P 104
None
None
None
FAD  P 449 ( 4.5A)
None
0.95A 6a5zL-3fg2P:
undetectable
6a5zL-3fg2P:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
5 / 12 ILE P 245
ALA P 248
ALA P 249
ILE P  32
LEU P 104
None
None
None
FAD  P 449 ( 4.5A)
None
0.99A 6a60D-3fg2P:
undetectable
6a60D-3fg2P:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
3 / 3 PHE P  61
ARG P  42
ALA P 105
None
FAD  P 449 (-3.7A)
FAD  P 449 (-4.7A)
0.84A 6ecfB-3fg2P:
undetectable
6ecfB-3fg2P:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 8 HIS P  37
SER P  58
SER P  52
ASP P 130
None
1.16A 6fboA-3fg2P:
undetectable
6fboA-3fg2P:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris)
4 / 8 HIS P  37
SER P  58
SER P  52
ASP P 130
None
1.20A 6fcdA-3fg2P:
undetectable
6fcdA-3fg2P:
13.30