SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.77A 1a7yB-3fg6A:
undetectable		 1a7yB-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.85A 1a7yB-3fg6A:
undetectable		 1a7yB-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.85A 1dscC-3fg6A:
undetectable		 1dscC-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.84A 1fjaC-3fg6A:
undetectable		 1fjaC-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.84A 1fjaD-3fg6A:
undetectable		 1fjaD-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.82A 1i3wE-3fg6A:
undetectable		 1i3wE-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.84A 1i3wG-3fg6A:
undetectable		 1i3wG-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.83A 1i3wG-3fg6A:
undetectable		 1i3wG-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.82A 1i3wH-3fg6A:
undetectable		 1i3wH-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.76A 1unjF-3fg6A:
undetectable		 1unjF-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.78A 1unjL-3fg6A:
undetectable		 1unjL-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.84A 1unjL-3fg6A:
undetectable		 1unjL-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.80A 1unjR-3fg6A:
undetectable		 1unjR-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.83A 1unjR-3fg6A:
undetectable		 1unjR-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.82A 1unjW-3fg6A:
undetectable		 1unjW-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.79A 1unjX-3fg6A:
undetectable		 1unjX-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.84A 1unjX-3fg6A:
undetectable		 1unjX-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.78A 1unmE-3fg6A:
undetectable		 1unmE-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.85A 1unmE-3fg6A:
undetectable		 1unmE-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.86A 1unmF-3fg6A:
undetectable		 1unmF-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.84A 1unmF-3fg6A:
undetectable		 1unmF-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 702
THR A 704
PRO A 700
 None
 0.77A 209dC-3fg6A:
undetectable		 209dC-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.66A 316dC-3fg6A:
undetectable		 316dC-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3fg6 ADSEVERIN
(Homo
sapiens) 		5 / 9 ALA A 674
ILE A 654
PHE A 655
PHE A 626
GLU A 669
 None
 1.48A 3qelD-3fg6A:
undetectable		 3qelD-3fg6A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 THR A 704
PRO A 700
THR A 702
 None
 0.79A 4hivD-3fg6A:
undetectable		 4hivD-3fg6A:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 GLU A 563
ARG A 579
GLN A 608
 None
 0.97A 4rtbA-3fg6A:
undetectable		 4rtbA-3fg6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 6 ARG A 408
ILE A 409
GLN A 410
ILE A 426
 None
 1.14A 4w5qA-3fg6A:
undetectable		 4w5qA-3fg6A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 6 ARG A 408
ILE A 409
GLN A 410
ILE A 426
 None
 1.14A 4w5tA-3fg6A:
undetectable		 4w5tA-3fg6A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 6 ARG A 408
ILE A 409
GLN A 410
ILE A 426
 None
 1.14A 4z4cA-3fg6A:
undetectable		 4z4cA-3fg6A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 6 SER A 537
GLU A 606
ASP A 529
GLY A 709
 None
 0.90A 5cdnC-3fg6A:
undetectable
5cdnD-3fg6A:
undetectable		 5cdnC-3fg6A:
21.98
5cdnD-3fg6A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 6 SER A 537
GLU A 606
ASP A 529
GLY A 709
 None
 0.89A 5cdnT-3fg6A:
undetectable
5cdnU-3fg6A:
undetectable		 5cdnT-3fg6A:
21.98
5cdnU-3fg6A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 TRP A 715
GLU A 642
ASP A 638
 None
 0.95A 5gqbA-3fg6A:
undetectable		 5gqbA-3fg6A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 3fg6 ADSEVERIN
(Homo
sapiens) 		5 / 11 ILE A 580
PHE A 589
VAL A 540
VAL A 542
LEU A 535
 None
 1.06A 5jkwA-3fg6A:
undetectable		 5jkwA-3fg6A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3fg6 ADSEVERIN
(Homo
sapiens) 		3 / 3 VAL A 473
SER A 474
TRP A 440
 None
 0.92A 5jwaA-3fg6A:
undetectable		 5jwaA-3fg6A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 8 LEU A 543
TYR A 551
GLU A 588
THR A 510
 None
 1.12A 6c71B-3fg6A:
undetectable		 6c71B-3fg6A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 6 ARG A 408
ILE A 409
GLN A 410
ILE A 426
 None
 1.13A 6cbdA-3fg6A:
undetectable		 6cbdA-3fg6A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3fg6 ADSEVERIN
(Homo
sapiens) 		4 / 7 TYR A 425
TYR A 494
TRP A 440
LEU A 491
 None
 1.27A 6cnkB-3fg6A:
undetectable
6cnkC-3fg6A:
undetectable		 6cnkB-3fg6A:
12.50
6cnkC-3fg6A:
13.51