SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
5 / 11 VAL A 121
LEU A 119
LEU A  37
THR A  35
THR A  36
None
1.22A 1dmyA-3fg9A:
undetectable
1dmyA-3fg9A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
5 / 12 TYR A  81
VAL A  19
ASP A  20
SER A  27
ASN A  24
None
None
FMT  A 155 ( 4.9A)
None
FMT  A 155 (-4.4A)
1.39A 2dcfA-3fg9A:
undetectable
2dcfA-3fg9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
3 / 3 ARG A  14
GLN A  92
PRO A  44
MG  A 154 ( 4.3A)
None
None
0.85A 2qhfA-3fg9A:
undetectable
2qhfA-3fg9A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
5 / 11 SER A  26
SER A  27
ALA A  30
LEU A 141
LEU A 120
None
1.02A 2xn5A-3fg9A:
undetectable
2xn5A-3fg9A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
5 / 12 GLY A 123
GLY A 138
LEU A 141
PHE A 128
ILE A 137
None
1.11A 2y7kD-3fg9A:
2.1
2y7kD-3fg9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
3 / 3 ALA A 136
ARG A 140
LYS A 144
None
0.91A 3kp5B-3fg9A:
undetectable
3kp5B-3fg9A:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
5 / 10 LEU A 119
VAL A 121
LEU A  37
THR A  35
THR A  36
None
1.04A 4e3hA-3fg9A:
undetectable
4e3hA-3fg9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)
3fg9 PROTEIN OF UNIVERSAL
STRESS PROTEIN USPA
FAMILY

(Lactobacillus
plantarum)
5 / 12 LEU A  84
PHE A  31
ALA A  38
GLY A  46
LEU A  45
None
1.30A 4j7xB-3fg9A:
3.2
4j7xB-3fg9A:
18.37