SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fgt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		5 / 9 LEU A 118
LEU A 205
VAL A 126
GLY A 124
ALA A  90
 NAG  A  11 ( 4.3A)
None
None
None
None
 1.25A 1e7aA-3fgtA:
undetectable		 1e7aA-3fgtA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus;
Mus
musculus) 		3 / 3 GLN A 186
HIS A 185
ARG B 287
 None
 0.99A 1zlqA-3fgtA:
undetectable		 1zlqA-3fgtA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		5 / 10 GLU B 350
ASN B 381
GLU A 232
LEU A 235
TYR A 156
 None
NA  B 606 ( 4.8A)
None
None
ACT  A   1 ( 4.7A)
 1.41A 2ha6A-3fgtB:
undetectable		 2ha6A-3fgtB:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		3 / 3 TRP A 170
GLN B 343
TRP B 351
 None
 1.04A 2vqyA-3fgtA:
undetectable		 2vqyA-3fgtA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 7 TYR A 146
LEU A 164
ASN A 167
TYR A 156
 ACT  A   1 (-4.0A)
None
None
ACT  A   1 ( 4.7A)
 1.46A 2w98A-3fgtA:
undetectable
2w98B-3fgtA:
undetectable		 2w98A-3fgtA:
18.16
2w98B-3fgtA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		5 / 12 LEU B 284
ASN B 300
LEU B 320
GLY B 321
MET B 549
 None
 1.32A 2yhdA-3fgtB:
undetectable		 2yhdA-3fgtB:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		5 / 12 PHE B 391
ALA B 390
THR B 419
GLY B 364
ARG B 401
 None
 1.18A 3aobC-3fgtB:
undetectable		 3aobC-3fgtB:
16.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FGR_A_ACTA22_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 4 TRP A 170
ARG A 173
GLU A 174
LEU A 177
 None
 0.21A 3fgrA-3fgtA:
28.3		 3fgrA-3fgtA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		4 / 4 ARG B 469
ASP B 488
ASP B 492
PRO B 493
 7PE  B 607 (-3.4A)
None
7PE  B 607 ( 4.1A)
None
 0.15A 3fgrB-3fgtB:
58.4		 3fgrB-3fgtB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus;
Mus
musculus) 		5 / 7 ALA B 553
ILE B 589
TRP A 103
ARG B 485
GLY A 102
 None
 1.38A 3v4tH-3fgtB:
undetectable		 3v4tH-3fgtB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 8 ARG A 173
ARG A 211
GLU A 176
GLU A 174
 None
 1.04A 4bqfB-3fgtA:
undetectable		 4bqfB-3fgtA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR8_A_TNGA601_1
(ALDEHYDE
DEHYDROGENASE,
MITOCHONDRIAL)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		5 / 11 PHE A 163
LEU A 235
CYH B 347
SER B 376
ASP A 227
 None
 1.49A 4fr8A-3fgtA:
undetectable		 4fr8A-3fgtA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus;
Mus
musculus) 		4 / 7 ILE A 224
LEU B 349
LYS A 159
PHE A 163
 None
None
NAG  A  21 (-2.7A)
None
 0.94A 4hajA-3fgtA:
undetectable		 4hajA-3fgtA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		5 / 11 PRO B 410
PHE A 163
ASP A 230
ASP A 227
ILE A 224
 None
 1.23A 4ktvC-3fgtB:
undetectable
4ktvD-3fgtB:
undetectable		 4ktvC-3fgtB:
20.37
4ktvD-3fgtB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		4 / 8 SER B 305
HIS B 266
TYR B 307
GLU B 328
 None
OCS  B 249 ( 4.3A)
None
NA  B 606 (-2.7A)
 1.27A 4ms4A-3fgtB:
undetectable		 4ms4A-3fgtB:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		4 / 8 SER B 305
HIS B 266
TYR B 307
ILE B 536
 None
OCS  B 249 ( 4.3A)
None
None
 1.35A 4ms4A-3fgtB:
undetectable		 4ms4A-3fgtB:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		4 / 6 LEU B 276
ASN A  96
LEU A  94
GLU A 127
 None
 1.02A 4nc3A-3fgtB:
undetectable		 4nc3A-3fgtB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		3 / 3 LEU B 252
MET B 477
TYR B 486
 None
None
GOL  B   5 (-4.2A)
 0.62A 4p6xG-3fgtB:
undetectable		 4p6xG-3fgtB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		4 / 6 GLN B 408
THR B 268
HIS B 266
ASN B 354
 None
OCS  B 249 ( 4.0A)
OCS  B 249 ( 4.3A)
None
 1.37A 4pfjB-3fgtB:
undetectable		 4pfjB-3fgtB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		5 / 12 ALA B 357
THR B 419
THR B 404
VAL B 402
LEU B 324
 None
 1.25A 4qzuA-3fgtB:
undetectable		 4qzuA-3fgtB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		5 / 11 LEU A  80
GLY A 124
LEU A 197
SER A 131
PHE A 219
 None
 1.36A 4wnuC-3fgtA:
undetectable		 4wnuC-3fgtA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		4 / 7 LEU B 255
TYR B 427
LEU B 422
GLU B 421
 None
 0.98A 4z4fA-3fgtB:
undetectable		 4z4fA-3fgtB:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus) 		5 / 12 TYR B 379
TRP B 428
ILE B 385
THR B 326
VAL B 415
 NA  B 606 (-4.5A)
None
None
None
None
 1.39A 5l8oB-3fgtB:
0.6		 5l8oB-3fgtB:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 6 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.33A 5x7pA-3fgtA:
undetectable		 5x7pA-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 6 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.26A 5x7pB-3fgtA:
undetectable		 5x7pB-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 6 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.31A 5x7qA-3fgtA:
undetectable		 5x7qA-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 6 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.32A 5x7qB-3fgtA:
undetectable		 5x7qB-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 6 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.29A 5x7rA-3fgtA:
undetectable		 5x7rA-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
(Mus
musculus) 		4 / 6 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.29A 5x7rB-3fgtA:
undetectable		 5x7rB-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus;
Mus
musculus) 		4 / 8 TRP B 584
TRP B 567
HIS A 138
THR A 142
 None
 1.47A 5yj1G-3fgtB:
undetectable
5yj1Y-3fgtB:
undetectable		 5yj1G-3fgtB:
16.05
5yj1Y-3fgtB:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus;
Mus
musculus) 		4 / 4 VAL B 342
GLY B 377
ASP A 230
ASP A 227
 None
 1.29A 6cjkC-3fgtB:
undetectable		 6cjkC-3fgtB:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM
(Mus
musculus;
Mus
musculus) 		3 / 3 LEU B 276
GLN B 580
LYS A  60
 None
 0.99A 6exiB-3fgtB:
undetectable		 6exiB-3fgtB:
12.97