SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fgx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		3 / 3 MET A  63
MET A 100
PHE A  70
 None
 1.16A 3gn8A-3fgxA:
undetectable		 3gn8A-3fgxA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 9 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.89A 6ebpA-3fgxA:
undetectable		 6ebpA-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.93A 6ebpB-3fgxA:
undetectable		 6ebpB-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.91A 6ebpC-3fgxA:
undetectable		 6ebpC-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.93A 6ebpD-3fgxA:
undetectable		 6ebpD-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 11 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.95A 6ebzA-3fgxA:
undetectable		 6ebzA-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 11 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.91A 6ebzB-3fgxA:
undetectable		 6ebzB-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 11 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.93A 6ebzC-3fgxA:
undetectable		 6ebzC-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3fgx RBSTP2171
(Geobacillus
stearothermophil
us) 		5 / 11 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
 None
 0.93A 6ebzD-3fgxA:
undetectable		 6ebzD-3fgxA:
22.50