SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fh2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZF_A_TMQA170_1
(DIHYDROFOLATE
REDUCTASE)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		5 / 12 ALA A  45
LEU A  37
LEU A 112
THR A   6
LEU A  92
 None
 1.01A 1bzfA-3fh2A:
undetectable		 1bzfA-3fh2A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		3 / 3 LEU A  88
MET A   1
MET A  98
 None
 0.90A 2vavF-3fh2A:
undetectable		 2vavF-3fh2A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		3 / 3 GLU A  18
HIS A  39
GLU A  19
 None
 0.84A 2x45B-3fh2A:
undetectable		 2x45B-3fh2A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		3 / 3 GLU A  18
HIS A  39
GLU A  19
 None
 0.87A 2x45C-3fh2A:
undetectable		 2x45C-3fh2A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		5 / 12 ALA A   9
LEU A 108
LEU A 109
GLY A  95
HIS A 100
 None
 0.94A 4pxmA-3fh2A:
undetectable		 4pxmA-3fh2A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSE_C_HQEC1583_1
(UREASE SUBUNIT ALPHA)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		4 / 5 ILE A  38
GLN A  61
ARG A  60
GLU A  62
 None
 1.31A 5fseC-3fh2A:
undetectable		 5fseC-3fh2A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		4 / 6 VAL A  44
LYS A  47
ALA A  48
VAL A 138
 None
 0.64A 5i8fA-3fh2A:
undetectable		 5i8fA-3fh2A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		3 / 3 GLY A  36
LEU A  15
HIS A  39
 None
 0.63A 5u63A-3fh2A:
undetectable		 5u63A-3fh2A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3fh2 PROBABLE
ATP-DEPENDENT
PROTEASE (HEAT SHOCK
PROTEIN)
(Corynebacterium
glutamicum) 		3 / 3 GLY A  36
LEU A  15
HIS A  39
 None
 0.62A 5u63B-3fh2A:
undetectable		 5u63B-3fh2A:
20.56