SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fh6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3fh6 MALTOSE TRANSPORT
SYSTEM PERMEASE
PROTEIN MALF
(Escherichia
coli) 		3 / 3 PHE F 438
PHE F 281
PHE F 277
 None
 0.87A 2od9A-3fh6F:
undetectable		 2od9A-3fh6F:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3fh6 MALTOSE TRANSPORT
SYSTEM PERMEASE
PROTEIN MALF
(Escherichia
coli) 		3 / 3 PHE F 438
PHE F 281
PHE F 277
 None
 0.87A 2qqgA-3fh6F:
undetectable		 2qqgA-3fh6F:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3fh6 MALTOSE TRANSPORT
SYSTEM PERMEASE
PROTEIN MALF
(Escherichia
coli) 		5 / 12 LEU F 302
VAL F 301
VAL F 375
PHE F 287
ASN F 437
 None
 1.45A 2y00A-3fh6F:
undetectable		 2y00A-3fh6F:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3fh6 MALTOSE TRANSPORT
SYSTEM PERMEASE
PROTEIN MALF
(Escherichia
coli) 		4 / 7 ASN F 440
LEU F 446
LEU F 379
PHE F 436
 None
 1.18A 3nk2X-3fh6F:
undetectable		 3nk2X-3fh6F:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3fh6 MALTOSE TRANSPORT
SYSTEM PERMEASE
PROTEIN MALF
(Escherichia
coli) 		4 / 6 PHE F 281
SER F 288
LEU F 466
LEU F 467
 None
 1.25A 5dzke-3fh6F:
undetectable
5dzks-3fh6F:
undetectable		 5dzke-3fh6F:
19.65
5dzks-3fh6F:
2.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3fh6 MALTOSE TRANSPORT
SYSTEM PERMEASE
PROTEIN MALF
(Escherichia
coli) 		4 / 6 ILE F 333
GLY F 345
ASN F 341
ILE F 335
 None
 0.96A 5j4nB-3fh6F:
undetectable		 5j4nB-3fh6F:
24.34