SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3fh9 HEMOGLOBIN ALPHA
CHAIN
(Pteropus
giganteus) 		5 / 10 LEU A 105
VAL A  21
VAL A  62
GLY A  63
LEU A 109
 None
None
HEM  A 142 (-4.0A)
None
None
 1.38A 1fkoA-3fh9A:
undetectable		 1fkoA-3fh9A:
13.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 3fh9 HEMOGLOBIN ALPHA
CHAIN
(Pteropus
giganteus) 		6 / 6 ALA A  57
LYS A  60
LYS A  61
ASP A  64
ALA A  65
LEU A  83
 None
None
HEM  A 142 (-3.7A)
None
HEM  A 142 ( 3.9A)
HEM  A 142 (-4.8A)
 1.01A 1iwhA-3fh9A:
24.9		 1iwhA-3fh9A:
87.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3fh9 HEMOGLOBIN ALPHA
CHAIN
(Pteropus
giganteus) 		4 / 7 PHE A  43
PHE A  46
VAL A  62
HIS A  87
 HEM  A 142 ( 3.8A)
None
HEM  A 142 (-4.0A)
HEM  A 142 (-3.4A)
 0.89A 1lh6A-3fh9A:
12.7		 1lh6A-3fh9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3fh9 HEMOGLOBIN ALPHA
CHAIN
(Pteropus
giganteus) 		3 / 3 PHE A  46
SER A  52
GLN A  54
 None
 0.81A 3smtA-3fh9A:
undetectable		 3smtA-3fh9A:
16.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3fh9 HEMOGLOBIN ALPHA
CHAIN
(Pteropus
giganteus) 		4 / 8 PRO A  95
ALA A 130
THR A 134
THR A 137
 None
 0.55A 5x2tI-3fh9A:
24.3
5x2tJ-3fh9A:
20.1
5x2tK-3fh9A:
24.5
5x2tL-3fh9A:
18.8		 5x2tI-3fh9A:
86.52
5x2tJ-3fh9A:
44.59
5x2tK-3fh9A:
86.52
5x2tL-3fh9A:
44.59