SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fha'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 5 ARG A 223
ALA A 215
ASP A 210
GLY A 212
 None
 0.71A 1e7bA-3fhaA:
undetectable		 1e7bA-3fhaA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		3 / 3 LEU A 121
HIS A 114
ILE A 110
 None
 0.67A 1s9pB-3fhaA:
undetectable		 1s9pB-3fhaA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 5 SER A  57
GLU A 318
TYR A  83
SER A 307
 None
 1.44A 1vidA-3fhaA:
undetectable		 1vidA-3fhaA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		3 / 3 THR A 362
GLU A 318
HIS A  85
 None
 0.92A 1xwfA-3fhaA:
undetectable		 1xwfA-3fhaA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		3 / 3 THR A 362
GLU A 318
HIS A  85
 None
 0.91A 1xwfC-3fhaA:
undetectable		 1xwfC-3fhaA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 6 LEU A   7
ASN A   4
SER A  70
PHE A  29
 None
PO4  A 707 (-3.9A)
None
None
 1.38A 3i9jB-3fhaA:
undetectable		 3i9jB-3fhaA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 8 SER A 452
ASP A 457
VAL A 460
LEU A 521
 None
 1.03A 3jq7C-3fhaA:
undetectable		 3jq7C-3fhaA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 10 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.23A 3lxiA-3fhaA:
undetectable		 3lxiA-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 11 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.24A 3lxiB-3fhaA:
undetectable		 3lxiB-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 7 ALA A 267
VAL A 280
VAL A 269
LEU A 296
 None
 0.88A 3o14A-3fhaA:
undetectable		 3o14A-3fhaA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 7 TRP A 204
LEU A 138
LEU A 135
ILE A 214
 None
 1.00A 3u5jA-3fhaA:
undetectable		 3u5jA-3fhaA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		3 / 3 SER A 232
GLY A 231
GLN A 229
 None
 0.38A 3v4tH-3fhaA:
undetectable		 3v4tH-3fhaA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		3 / 3 ASP A 543
GLU A 584
GLY A 585
 None
 0.66A 3w9tA-3fhaA:
undetectable		 3w9tA-3fhaA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 9 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.25A 4c9kA-3fhaA:
undetectable		 4c9kA-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 9 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.25A 4c9kB-3fhaA:
undetectable		 4c9kB-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 8 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.23A 4c9nA-3fhaA:
undetectable		 4c9nA-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 10 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.20A 4c9nB-3fhaA:
undetectable		 4c9nB-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 9 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.25A 4c9pA-3fhaA:
undetectable		 4c9pA-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 10 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.28A 4c9pB-3fhaA:
undetectable		 4c9pB-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 11 PHE A 360
PHE A 450
PHE A 504
LEU A 433
ALA A 429
 None
 1.46A 4dx7A-3fhaA:
undetectable		 4dx7A-3fhaA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 7 ILE A 431
LEU A 433
PHE A 360
GLY A 519
 None
 0.96A 4hajA-3fhaA:
undetectable		 4hajA-3fhaA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		3 / 3 GLU A 412
TYR A 563
GLU A 600
 None
 0.69A 4ryaA-3fhaA:
undetectable		 4ryaA-3fhaA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 12 TYR A 299
ALA A  94
ALA A  60
ASN A 123
TYR A 205
 None
 1.36A 4u14A-3fhaA:
undetectable		 4u14A-3fhaA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 12 TYR A 299
ALA A  94
ALA A  60
ASN A 123
TYR A 205
 None
 1.36A 4u15B-3fhaA:
undetectable		 4u15B-3fhaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 8 ASP A 302
SER A  57
ARG A 300
TRP A 282
 None
 1.12A 4uhxA-3fhaA:
2.6		 4uhxA-3fhaA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 8 GLU A 318
ASP A 302
ARG A 300
TRP A 282
 None
 1.08A 4uhxA-3fhaA:
2.6		 4uhxA-3fhaA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 11 PHE A 356
ALA A 351
LEU A 417
LEU A 521
LEU A 433
 None
 1.14A 4zmeA-3fhaA:
undetectable		 4zmeA-3fhaA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 10 PHE A 356
ALA A 351
LEU A 417
LEU A 521
LEU A 433
 None
 1.12A 4zmeB-3fhaA:
undetectable		 4zmeB-3fhaA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 5 SER A  57
GLU A 318
TYR A  83
SER A 307
 None
 1.42A 5fhrA-3fhaA:
undetectable		 5fhrA-3fhaA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		5 / 12 ALA A  94
GLY A  95
SER A  96
GLU A  14
GLU A 136
 None
 1.21A 5nwuA-3fhaA:
undetectable		 5nwuA-3fhaA:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Glutamicibacter
protophormiae) 		4 / 5 LEU A 597
VAL A 595
GLU A 588
LEU A 586
 None
 1.09A 5xooB-3fhaA:
undetectable		 5xooB-3fhaA:
8.75