SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fhl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 4 ALA A   9
VAL A  35
ALA A  10
HIS A  19
 None
 1.17A 1q23A-3fhlA:
undetectable		 1q23A-3fhlA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 4 ALA A   9
VAL A  35
ALA A  10
HIS A  19
 None
 1.17A 1q23K-3fhlA:
undetectable		 1q23K-3fhlA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 5 THR A 150
ARG A 241
ALA A 152
ARG A 153
 None
 1.36A 2qhfA-3fhlA:
undetectable		 2qhfA-3fhlA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 12 ILE A 214
ILE A 213
GLY A 200
ALA A 197
VAL A 208
 None
 0.98A 2yvlB-3fhlA:
4.6		 2yvlB-3fhlA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 9 GLY A 103
GLN A 102
ILE A 329
VAL A 119
VAL A  92
 None
 1.36A 3fi0N-3fhlA:
undetectable		 3fi0N-3fhlA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 8 TYR A 305
ASP A 126
PHE A  18
GLY A 255
 None
 0.78A 3ihzB-3fhlA:
undetectable		 3ihzB-3fhlA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		6 / 12 ASN A 311
GLY A 306
GLY A 307
ASN A 304
LEU A 322
GLY A 303
 None
 1.43A 4e3aB-3fhlA:
4.5		 4e3aB-3fhlA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 8 GLY A 178
LEU A 181
ILE A 182
ILE A 214
 None
 0.71A 4em2A-3fhlA:
undetectable		 4em2A-3fhlA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 8 ASN A 122
ASP A 126
PHE A  18
VAL A  17
 None
 1.23A 4f5zA-3fhlA:
4.4		 4f5zA-3fhlA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 8 GLY A  87
GLY A  81
GLU A  85
TYR A  77
LEU A 106
 None
 1.42A 4fgzA-3fhlA:
undetectable		 4fgzA-3fhlA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 5 ILE A 182
ASN A 176
TYR A 175
ILE A 336
 None
 1.07A 4jtpA-3fhlA:
undetectable		 4jtpA-3fhlA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 9 ALA A  80
ALA A  83
LEU A  58
SER A 118
LEU A 117
 None
 1.12A 4or0A-3fhlA:
undetectable		 4or0A-3fhlA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 9 ALA A  80
ALA A  83
LEU A  58
SER A 118
LEU A 117
 None
 1.10A 4or0B-3fhlA:
undetectable		 4or0B-3fhlA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 12 ALA A  49
THR A  71
GLY A  15
SER A  14
SER A  42
 None
 1.25A 5hfjF-3fhlA:
2.7		 5hfjF-3fhlA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 6 TYR A 309
HIS A  19
ILE A  34
TYR A  46
 None
 0.93A 5ih0A-3fhlA:
undetectable		 5ih0A-3fhlA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 12 PHE A 308
LEU A  31
THR A   6
LEU A  66
PHE A  29
 None
 1.23A 5xxiA-3fhlA:
undetectable		 5xxiA-3fhlA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 6 PHE A 189
VAL A 132
LEU A 141
LEU A 144
 None
 0.99A 6e43A-3fhlA:
undetectable		 6e43A-3fhlA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 6 PHE A 189
VAL A 132
LEU A 141
LEU A 144
 None
 1.00A 6e43B-3fhlA:
undetectable		 6e43B-3fhlA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		4 / 6 PHE A 189
VAL A 132
LEU A 141
LEU A 144
 None
 0.98A 6e43C-3fhlA:
undetectable		 6e43C-3fhlA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 11 GLY A  15
LEU A  31
ALA A  49
PHE A  11
SER A  42
 None
 1.42A 6qgbA-3fhlA:
0.5		 6qgbA-3fhlA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 10 GLY A  15
LEU A  31
ALA A  49
PHE A  11
SER A  42
 None
 1.39A 6qgbB-3fhlA:
3.9		 6qgbB-3fhlA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 10 GLY A  15
LEU A  31
ALA A  49
PHE A  11
SER A  42
 None
 1.41A 6qgbD-3fhlA:
3.5		 6qgbD-3fhlA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 11 GLY A  15
LEU A  31
ALA A  49
PHE A  11
SER A  42
 None
 1.39A 6qgbE-3fhlA:
undetectable		 6qgbE-3fhlA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3fhl PUTATIVE
OXIDOREDUCTASE
(Bacteroides
fragilis) 		5 / 10 GLY A  15
LEU A  31
ALA A  49
PHE A  11
SER A  42
 None
 1.44A 6qgbF-3fhlA:
0.0		 6qgbF-3fhlA:
21.26