SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 567
MET A 458
TYR A 455
LEU A 574
 None
 0.94A 1kt3A-3fhnA:
undetectable		 1kt3A-3fhnA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 595
ASP A 620
PHE A 617
 None
 0.55A 1uwjB-3fhnA:
undetectable		 1uwjB-3fhnA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.17A 1v55C-3fhnA:
3.9
1v55N-3fhnA:
2.6
1v55P-3fhnA:
3.9		 1v55C-3fhnA:
16.62
1v55N-3fhnA:
20.97
1v55P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 650
ASP A 620
ASN A 615
 None
 0.78A 2bm9A-3fhnA:
undetectable		 2bm9A-3fhnA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 674
PHE A 671
LEU A 651
LEU A 661
ALA A 691
 None
 1.35A 2bxeA-3fhnA:
undetectable		 2bxeA-3fhnA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		6 / 12 GLY A 349
LEU A 335
GLY A 351
LEU A 342
ILE A 356
LEU A 410
 None
 1.08A 2nxeA-3fhnA:
undetectable		 2nxeA-3fhnA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.19A 2y69C-3fhnA:
3.9
2y69N-3fhnA:
undetectable
2y69P-3fhnA:
3.9		 2y69C-3fhnA:
16.62
2y69N-3fhnA:
20.97
2y69P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 518
LEU A 628
ASN A 636
LEU A 574
ILE A 571
 None
 1.35A 3a50B-3fhnA:
undetectable		 3a50B-3fhnA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.11A 3ablA-3fhnA:
3.5
3ablC-3fhnA:
3.8
3ablP-3fhnA:
3.8		 3ablA-3fhnA:
20.97
3ablC-3fhnA:
16.62
3ablP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.12A 3ablC-3fhnA:
3.8
3ablN-3fhnA:
2.7
3ablP-3fhnA:
3.8		 3ablC-3fhnA:
16.62
3ablN-3fhnA:
20.97
3ablP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.13A 3abmA-3fhnA:
4.3
3abmC-3fhnA:
3.9
3abmP-3fhnA:
3.9		 3abmA-3fhnA:
20.97
3abmC-3fhnA:
16.62
3abmP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.14A 3asnC-3fhnA:
3.9
3asnN-3fhnA:
3.6
3asnP-3fhnA:
3.0		 3asnC-3fhnA:
16.62
3asnN-3fhnA:
20.97
3asnP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.18A 3asoA-3fhnA:
1.4
3asoC-3fhnA:
3.9
3asoP-3fhnA:
3.9		 3asoA-3fhnA:
20.97
3asoC-3fhnA:
16.62
3asoP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.16A 3asoC-3fhnA:
3.9
3asoN-3fhnA:
2.7
3asoP-3fhnA:
3.9		 3asoC-3fhnA:
16.62
3asoN-3fhnA:
20.97
3asoP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 207
GLN A 162
HIS A 122
LEU A 212
 None
 1.25A 3ce6D-3fhnA:
undetectable		 3ce6D-3fhnA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 335
GLY A 351
LEU A 342
ILE A 356
LEU A 410
 None
 0.98A 3cjtG-3fhnA:
undetectable		 3cjtG-3fhnA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 335
GLY A 351
LEU A 342
ILE A 356
LEU A 410
 None
 1.00A 3cjtO-3fhnA:
undetectable		 3cjtO-3fhnA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 GLN A 452
GLN A 456
ALA A 459
LEU A 439
 None
 0.70A 3ozwA-3fhnA:
undetectable		 3ozwA-3fhnA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		3 / 3 TYR A 637
LEU A 624
LYS A 622
 None
 0.74A 3sueD-3fhnA:
undetectable		 3sueD-3fhnA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.18A 3wg7A-3fhnA:
3.8
3wg7C-3fhnA:
3.9
3wg7P-3fhnA:
3.6		 3wg7A-3fhnA:
20.97
3wg7C-3fhnA:
16.62
3wg7P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.19A 3wg7C-3fhnA:
3.9
3wg7N-3fhnA:
3.9
3wg7P-3fhnA:
3.5		 3wg7C-3fhnA:
16.62
3wg7N-3fhnA:
20.97
3wg7P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.15A 3x2qA-3fhnA:
undetectable
3x2qC-3fhnA:
3.8
3x2qP-3fhnA:
3.8		 3x2qA-3fhnA:
20.97
3x2qC-3fhnA:
16.62
3x2qP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.14A 3x2qC-3fhnA:
3.8
3x2qN-3fhnA:
undetectable
3x2qP-3fhnA:
3.8		 3x2qC-3fhnA:
16.62
3x2qN-3fhnA:
20.97
3x2qP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 568
ASP A 620
GLN A 616
 None
 0.93A 4azsA-3fhnA:
undetectable		 4azsA-3fhnA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 11 TRP A 361
LEU A 415
ASP A 338
LEU A 352
GLY A 351
 None
 1.09A 4fogD-3fhnA:
undetectable		 4fogD-3fhnA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 12 TRP A 361
LEU A 415
ASP A 338
LEU A 352
GLY A 351
 None
 1.20A 4foxA-3fhnA:
undetectable		 4foxA-3fhnA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 252
ARG A 251
PHE A 248
TYR A 275
 None
 1.50A 4uciA-3fhnA:
undetectable		 4uciA-3fhnA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 252
ARG A 251
PHE A 248
TYR A 275
 None
 1.50A 4uciB-3fhnA:
undetectable		 4uciB-3fhnA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPE_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 669
ASP A 690
TYR A 693
LYS A 675
ILE A 648
 None
 1.13A 4ypeA-3fhnA:
undetectable		 4ypeA-3fhnA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.22A 5b1aA-3fhnA:
3.8
5b1aC-3fhnA:
3.9
5b1aP-3fhnA:
3.9		 5b1aA-3fhnA:
20.97
5b1aC-3fhnA:
16.62
5b1aP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 251
THR A 183
ASP A 182
 None
 0.66A 5g5gA-3fhnA:
undetectable
5g5gB-3fhnA:
undetectable		 5g5gA-3fhnA:
15.10
5g5gB-3fhnA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.13A 5iy5C-3fhnA:
3.9
5iy5N-3fhnA:
3.8
5iy5P-3fhnA:
3.4		 5iy5C-3fhnA:
16.43
5iy5N-3fhnA:
20.97
5iy5P-3fhnA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 247
TYR A 275
CYH A 283
 None
 1.06A 5lsuB-3fhnA:
undetectable		 5lsuB-3fhnA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 10 TYR A 506
ILE A 518
ILE A 522
LEU A 525
HIS A 463
 None
 1.40A 5vkqA-3fhnA:
4.9
5vkqD-3fhnA:
4.8		 5vkqA-3fhnA:
17.55
5vkqD-3fhnA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 10 HIS A 463
TYR A 506
ILE A 518
ILE A 522
LEU A 525
 None
 1.41A 5vkqA-3fhnA:
4.9
5vkqB-3fhnA:
4.9		 5vkqA-3fhnA:
17.55
5vkqB-3fhnA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 10 HIS A 463
TYR A 506
ILE A 518
ILE A 522
LEU A 525
 None
 1.38A 5vkqC-3fhnA:
4.9
5vkqD-3fhnA:
4.8		 5vkqC-3fhnA:
17.55
5vkqD-3fhnA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		5 / 8 ASP A 620
HIS A 643
GLN A 616
GLY A 613
LEU A 614
 None
 1.45A 5w3jB-3fhnA:
undetectable		 5w3jB-3fhnA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.13A 5w97A-3fhnA:
2.7
5w97C-3fhnA:
3.5
5w97c-3fhnA:
3.5		 5w97A-3fhnA:
20.97
5w97C-3fhnA:
16.62
5w97c-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.19A 5w97C-3fhnA:
3.5
5w97a-3fhnA:
2.7
5w97c-3fhnA:
3.5		 5w97C-3fhnA:
16.62
5w97a-3fhnA:
20.97
5w97c-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.15A 5wauA-3fhnA:
undetectable
5wauC-3fhnA:
3.9
5wauc-3fhnA:
3.9		 5wauA-3fhnA:
20.97
5wauC-3fhnA:
16.62
5wauc-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.11A 5wauC-3fhnA:
3.9
5waua-3fhnA:
undetectable
5wauc-3fhnA:
3.9		 5wauC-3fhnA:
16.62
5waua-3fhnA:
20.97
5wauc-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.09A 5x19A-3fhnA:
2.6
5x19C-3fhnA:
3.5
5x19P-3fhnA:
3.8		 5x19A-3fhnA:
20.97
5x19C-3fhnA:
16.62
5x19P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.12A 5x1bA-3fhnA:
undetectable
5x1bC-3fhnA:
3.5
5x1bP-3fhnA:
3.4		 5x1bA-3fhnA:
20.97
5x1bC-3fhnA:
16.62
5x1bP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.07A 5x1fA-3fhnA:
2.9
5x1fC-3fhnA:
3.0
5x1fP-3fhnA:
2.5		 5x1fA-3fhnA:
20.97
5x1fC-3fhnA:
16.62
5x1fP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.16A 5xdqA-3fhnA:
undetectable
5xdqC-3fhnA:
3.9
5xdqP-3fhnA:
3.9		 5xdqA-3fhnA:
20.97
5xdqC-3fhnA:
16.62
5xdqP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.15A 5xdqC-3fhnA:
3.9
5xdqN-3fhnA:
3.4
5xdqP-3fhnA:
3.5		 5xdqC-3fhnA:
16.62
5xdqN-3fhnA:
20.97
5xdqP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.14A 5xdxC-3fhnA:
4.0
5xdxN-3fhnA:
3.6
5xdxP-3fhnA:
3.9		 5xdxC-3fhnA:
16.43
5xdxN-3fhnA:
20.97
5xdxP-3fhnA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.18A 5z84A-3fhnA:
1.5
5z84C-3fhnA:
3.9
5z84P-3fhnA:
3.9		 5z84A-3fhnA:
20.97
5z84C-3fhnA:
16.62
5z84P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.15A 5z84C-3fhnA:
3.9
5z84N-3fhnA:
3.7
5z84P-3fhnA:
3.9		 5z84C-3fhnA:
16.62
5z84N-3fhnA:
20.97
5z84P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.19A 5z85A-3fhnA:
3.6
5z85C-3fhnA:
3.9
5z85P-3fhnA:
3.9		 5z85A-3fhnA:
20.97
5z85C-3fhnA:
16.62
5z85P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.17A 5z85C-3fhnA:
3.9
5z85N-3fhnA:
3.8
5z85P-3fhnA:
3.9		 5z85C-3fhnA:
16.62
5z85N-3fhnA:
20.97
5z85P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.17A 5z86A-3fhnA:
3.8
5z86C-3fhnA:
3.9
5z86P-3fhnA:
3.8		 5z86A-3fhnA:
20.97
5z86C-3fhnA:
16.62
5z86P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.16A 5z86C-3fhnA:
3.9
5z86N-3fhnA:
undetectable
5z86P-3fhnA:
3.9		 5z86C-3fhnA:
16.62
5z86N-3fhnA:
20.97
5z86P-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.19A 5zcoA-3fhnA:
3.0
5zcoC-3fhnA:
3.9
5zcoP-3fhnA:
5.2		 5zcoA-3fhnA:
20.97
5zcoC-3fhnA:
16.62
5zcoP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.16A 5zcoC-3fhnA:
3.9
5zcoN-3fhnA:
3.6
5zcoP-3fhnA:
5.2		 5zcoC-3fhnA:
16.62
5zcoN-3fhnA:
20.97
5zcoP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.19A 5zcpA-3fhnA:
2.6
5zcpC-3fhnA:
3.9
5zcpP-3fhnA:
3.9		 5zcpA-3fhnA:
20.97
5zcpC-3fhnA:
16.62
5zcpP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.16A 5zcpC-3fhnA:
3.9
5zcpN-3fhnA:
3.6
5zcpP-3fhnA:
3.9		 5zcpC-3fhnA:
16.62
5zcpN-3fhnA:
20.97
5zcpP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.19A 5zcqA-3fhnA:
undetectable
5zcqC-3fhnA:
3.9
5zcqP-3fhnA:
3.9		 5zcqA-3fhnA:
20.97
5zcqC-3fhnA:
16.62
5zcqP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 661
ASP A 654
TYR A 653
HIS A 643
 None
 1.15A 6nknC-3fhnA:
3.8
6nknN-3fhnA:
undetectable
6nknP-3fhnA:
3.7		 6nknC-3fhnA:
16.62
6nknN-3fhnA:
20.97
6nknP-3fhnA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fhn PROTEIN TRANSPORT
PROTEIN TIP20
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 654
TYR A 653
HIS A 643
LEU A 661
 None
 1.14A 6nmfA-3fhnA:
3.9
6nmfC-3fhnA:
3.8
6nmfP-3fhnA:
3.7		 6nmfA-3fhnA:
20.97
6nmfC-3fhnA:
16.62
6nmfP-3fhnA:
16.62