SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fho'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		5 / 12 GLU A 336
ILE A 368
ASP A 375
ILE A 357
ARG A 371
 None
 1.43A 1kijA-3fhoA:
undetectable		 1kijA-3fhoA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU A 291
PRO A 309
ALA A 308
ILE A 157
 None
 1.05A 2aofB-3fhoA:
undetectable		 2aofB-3fhoA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A 389
ASP A 264
ASP A 261
 None
 1.04A 2br4A-3fhoA:
3.4		 2br4A-3fhoA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 8 LEU A 145
ARG A 177
SER A 160
VAL A 259
 None
 1.16A 2qd2A-3fhoA:
2.6		 2qd2A-3fhoA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_2
(TYROSINE-PROTEIN
KINASE ABL2)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 5 VAL A 421
ILE A 446
TYR A 330
MET A 331
 None
 1.16A 3gvuA-3fhoA:
undetectable		 3gvuA-3fhoA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A 325
ARG A 480
ASP A 417
 None
 1.45A 3o7wA-3fhoA:
3.1		 3o7wA-3fhoA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU A 382
ILE A 356
ALA A 380
PHE A 398
 None
 1.03A 4dc3B-3fhoA:
3.0		 4dc3B-3fhoA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		3 / 3 GLY A 239
PRO A 238
ALA A 191
 None
 0.51A 4qn9B-3fhoA:
undetectable		 4qn9B-3fhoA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		5 / 12 GLU A 336
ILE A 368
ASP A 375
ILE A 357
ARG A 371
 None
 1.38A 4uroA-3fhoA:
undetectable		 4uroA-3fhoA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		5 / 12 GLU A 336
ILE A 368
ASP A 375
ILE A 357
ARG A 371
 None
 1.30A 4uroD-3fhoA:
undetectable		 4uroD-3fhoA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 8 ILE A 200
ALA A 187
VAL A 259
VAL A 204
 None
 0.84A 5ecnD-3fhoA:
undetectable		 5ecnD-3fhoA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 8 VAL A 241
GLY A 273
GLN A 275
LEU A 272
 None
 0.93A 5sxqA-3fhoA:
undetectable		 5sxqA-3fhoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 8 VAL A 241
GLY A 273
GLN A 275
LEU A 272
 None
 0.90A 5sxtA-3fhoA:
undetectable		 5sxtA-3fhoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 8 VAL A 241
GLY A 273
GLN A 275
LEU A 272
 None
 0.89A 5sxtB-3fhoA:
undetectable		 5sxtB-3fhoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3fho ATP-DEPENDENT RNA
HELICASE DBP5
(Schizosaccharomy
ces
pombe) 		4 / 5 PHE A 296
THR A 318
GLU A 313
ASN A 310
 None
 1.47A 5ybbA-3fhoA:
undetectable		 5ybbA-3fhoA:
16.64