SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fi1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 12 ILE A 169
ILE A 168
ALA A 167
MET A 341
ILE A 134
 None
 1.13A 1xzxX-3fi1A:
undetectable		 1xzxX-3fi1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 12 ILE A 169
ILE A 168
ALA A 167
MET A 341
ILE A 134
 None
 1.06A 2h79A-3fi1A:
undetectable		 2h79A-3fi1A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		4 / 5 LEU A 348
ASP A 164
ALA A 127
PHE A  72
 None
 1.00A 2opxA-3fi1A:
undetectable		 2opxA-3fi1A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		4 / 8 ILE A 209
LEU A 194
VAL A 193
LEU A 197
 None
 0.90A 2w98B-3fi1A:
undetectable		 2w98B-3fi1A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 12 ILE A 169
ILE A 168
ALA A 167
MET A 341
ILE A 134
 None
 1.04A 3gwsX-3fi1A:
undetectable		 3gwsX-3fi1A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		4 / 5 LEU A  88
GLN A  85
LEU A  83
GLU A  82
 None
 0.97A 3h5gA-3fi1A:
undetectable
3h5gB-3fi1A:
undetectable		 3h5gA-3fi1A:
8.02
3h5gB-3fi1A:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 12 LEU A 348
VAL A 224
ILE A 168
ILE A 345
ALA A 130
 None
 1.08A 4ltwA-3fi1A:
undetectable		 4ltwA-3fi1A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		4 / 8 TYR A 112
LYS A 362
ILE A 128
ALA A 349
 None
 0.88A 4ou1A-3fi1A:
undetectable		 4ou1A-3fi1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 12 GLY A 212
ALA A 190
ILE A 209
VAL A 233
ILE A 237
 None
 1.05A 4uw0A-3fi1A:
undetectable		 4uw0A-3fi1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		4 / 8 GLY A 104
TYR A 112
GLY A 303
PHE A 307
 None
 0.73A 5albL-3fi1A:
undetectable		 5albL-3fi1A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 12 GLY A 166
ALA A 130
ALA A 160
ILE A 161
ALA A 172
 None
 1.09A 5bw4B-3fi1A:
undetectable		 5bw4B-3fi1A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 10 GLY A 230
GLY A  76
LEU A  73
LEU A 251
GLU A 252
 None
 1.36A 5hwkA-3fi1A:
undetectable		 5hwkA-3fi1A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 10 GLY A 230
GLY A  76
LEU A  73
LEU A 251
GLU A 252
 None
 1.35A 5hwkB-3fi1A:
undetectable		 5hwkB-3fi1A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		5 / 12 LEU A 152
PHE A 307
ALA A 100
ALA A 160
GLY A 336
 None
 1.05A 5veuB-3fi1A:
undetectable		 5veuB-3fi1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3fi1 NA(+)/H(+)
ANTIPORTER NHAA
(Escherichia
coli) 		4 / 7 PHE A 339
ALA A 131
GLY A 338
GLY A 336
 None
 0.75A 5ybbB-3fi1A:
undetectable		 5ybbB-3fi1A:
19.53