SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 3fi7 LMO1076 PROTEIN
(Listeria
monocytogenes) 		4 / 7 LEU A 180
ASN A 183
GLU A 122
LEU A 121
 None
 1.20A 2w8yA-3fi7A:
undetectable		 2w8yA-3fi7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3fi7 LMO1076 PROTEIN
(Listeria
monocytogenes) 		3 / 3 SER A 175
TYR A 173
TYR A 136
 None
 0.82A 5lakA-3fi7A:
undetectable
5lakI-3fi7A:
undetectable		 5lakA-3fi7A:
20.38
5lakI-3fi7A:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3fi7 LMO1076 PROTEIN
(Listeria
monocytogenes) 		3 / 3 SER A 175
TYR A 173
TYR A 136
 None
 0.84A 5lakC-3fi7A:
undetectable
5lakJ-3fi7A:
undetectable		 5lakC-3fi7A:
20.38
5lakJ-3fi7A:
3.81