SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 9 LEU A 207
ILE A 202
ARG A 218
VAL A 186
ALA A 188
 None
 1.28A 1e7aA-3fi9A:
undetectable		 1e7aA-3fi9A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 135
LEU A 132
GLY A 131
GLN A 144
ILE A 110
 None
 1.02A 1p93A-3fi9A:
undetectable		 1p93A-3fi9A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		3 / 3 ASN A 173
TYR A 177
SER A 189
 None
 0.91A 2gvcE-3fi9A:
undetectable		 2gvcE-3fi9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 PRO A 126
ILE A 321
LEU A 308
LEU A 132
ILE A 271
 None
 1.16A 3a50E-3fi9A:
undetectable		 3a50E-3fi9A:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		4 / 8 ILE A 102
LEU A 106
VAL A  12
GLY A  83
 None
 0.87A 3dcjB-3fi9A:
5.4		 3dcjB-3fi9A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A  47
GLY A  13
GLY A  16
GLY A  44
ILE A  11
 None
 0.99A 3eluA-3fi9A:
5.2		 3eluA-3fi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A  47
GLY A  13
GLY A  16
GLY A  44
ILE A  11
 None
 0.96A 3elwA-3fi9A:
5.4		 3elwA-3fi9A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 LEU A 106
GLY A 107
VAL A 145
ILE A 121
VAL A 120
 None
 1.04A 4c9lB-3fi9A:
undetectable		 4c9lB-3fi9A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		4 / 8 THR A 174
LEU A 198
VAL A 193
VAL A 171
 None
 0.89A 4em2A-3fi9A:
undetectable		 4em2A-3fi9A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		4 / 8 ASN A 173
ALA A 191
PRO A 197
LEU A 160
 None
 0.89A 4jjkA-3fi9A:
2.5		 4jjkA-3fi9A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		4 / 6 ILE A  11
GLY A  19
ILE A 243
LEU A  35
 None
 0.69A 4o8fB-3fi9A:
undetectable		 4o8fB-3fi9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		4 / 7 VAL A 171
PHE A 164
HIS A 163
GLU A 159
 None
 1.24A 5ad9A-3fi9A:
undetectable
5ad9B-3fi9A:
undetectable		 5ad9A-3fi9A:
21.79
5ad9B-3fi9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		3 / 3 TYR A  38
THR A  10
THR A  65
 None
 0.59A 5aoxB-3fi9A:
2.0		 5aoxB-3fi9A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		3 / 3 TYR A  38
THR A  10
THR A  65
 None
 0.58A 5aoxE-3fi9A:
undetectable		 5aoxE-3fi9A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		3 / 3 TYR A  77
LYS A  76
LYS A 118
 None
 1.32A 5dbyA-3fi9A:
undetectable		 5dbyA-3fi9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 ASP A 288
ASN A 290
LEU A 301
PHE A 268
ILE A 289
 None
 1.38A 5dv4A-3fi9A:
undetectable		 5dv4A-3fi9A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A  47
GLY A  13
GLY A  16
GLY A  44
ILE A  11
 None
 0.95A 5kqrA-3fi9A:
5.2		 5kqrA-3fi9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A  47
GLY A  13
GLY A  16
GLY A  44
ILE A  11
 None
 0.96A 5vimB-3fi9A:
5.2		 5vimB-3fi9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		4 / 7 ALA A  71
THR A  10
ILE A  11
ALA A  14
 None
 0.99A 6ma7A-3fi9A:
undetectable		 6ma7A-3fi9A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3fi9 MALATE DEHYDROGENASE
(Porphyromonas
gingivalis) 		3 / 3 THR A  25
GLU A  51
ASN A  21
 None
 0.77A 6nj9K-3fi9A:
5.4		 6nj9K-3fi9A:
20.27