SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 7 TYR A 212
GLY A 214
ILE A 182
GLY A 117
 None
 0.84A 11gsB-3fijA:
undetectable		 11gsB-3fijA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 8 PHE A 112
ILE A 114
LEU A 232
VAL A 215
 None
 0.91A 1fslA-3fijA:
undetectable		 1fslA-3fijA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 4 GLY A 117
LEU A 120
GLY A  69
ARG A 116
 None
 1.09A 1j7kA-3fijA:
undetectable		 1j7kA-3fijA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 11 LEU A  65
LEU A 105
ALA A 104
ALA A 124
VAL A 121
 None
 1.11A 3e22B-3fijA:
undetectable		 3e22B-3fijA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 11 LEU A  65
LEU A 105
ALA A 104
ALA A 124
VAL A 121
 None
 1.10A 3e22D-3fijA:
undetectable		 3e22D-3fijA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 6 PRO A  44
LEU A  66
LYS A  30
ALA A  36
 None
 1.22A 3gv1A-3fijA:
undetectable
3gv1C-3fijA:
undetectable		 3gv1A-3fijA:
22.99
3gv1C-3fijA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 6 LEU A  66
LYS A  30
ALA A  36
PRO A  44
 None
 1.16A 3gv1A-3fijA:
undetectable
3gv1B-3fijA:
undetectable		 3gv1A-3fijA:
22.99
3gv1B-3fijA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 9 LEU A  65
LEU A  61
ILE A  45
ALA A  46
ALA A  58
 None
 1.07A 3mdvA-3fijA:
undetectable		 3mdvA-3fijA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 5 GLU A  85
GLN A 180
HIS A 179
GLY A  87
 None
 1.19A 3pp1A-3fijA:
undetectable		 3pp1A-3fijA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 7 LEU A 125
GLY A 117
GLU A  97
ALA A 113
 None
 0.88A 3tehB-3fijA:
undetectable		 3tehB-3fijA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 11 GLY A  69
GLY A  70
HIS A 178
GLN A 180
HIS A 218
 None
None
MN  A 300 (-3.5A)
None
None
 1.09A 4l8fB-3fijA:
20.0		 4l8fB-3fijA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 12 ILE A  49
THR A  74
VAL A 123
SER A  95
GLN A 180
 None
 1.47A 4qztA-3fijA:
undetectable		 4qztA-3fijA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 12 ILE A 182
ALA A 186
TYR A  78
LEU A 129
LEU A 120
 None
 1.23A 4qztC-3fijA:
undetectable		 4qztC-3fijA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 8 LEU A  65
ALA A 104
ALA A 124
LEU A 120
LEU A  67
 None
 1.17A 4z90A-3fijA:
undetectable
4z90B-3fijA:
undetectable
4z90C-3fijA:
undetectable
4z90D-3fijA:
undetectable
4z90E-3fijA:
undetectable		 4z90A-3fijA:
21.92
4z90B-3fijA:
21.92
4z90C-3fijA:
21.92
4z90D-3fijA:
21.92
4z90E-3fijA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		5 / 8 LEU A 120
LEU A  67
LEU A  65
ALA A 104
ALA A 124
 None
 1.15A 4z90A-3fijA:
undetectable
4z90B-3fijA:
undetectable
4z90C-3fijA:
undetectable
4z90D-3fijA:
undetectable
4z90E-3fijA:
undetectable		 4z90A-3fijA:
21.92
4z90B-3fijA:
21.92
4z90C-3fijA:
21.92
4z90D-3fijA:
21.92
4z90E-3fijA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 6 SER A 229
ASN A 175
MET A 222
TRP A 217
 None
 1.11A 5j4nA-3fijA:
undetectable		 5j4nA-3fijA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3fij LIN1909 PROTEIN
(Listeria
innocua) 		4 / 6 SER A 229
GLY A 152
ASN A 175
MET A 222
 None
 1.01A 5j4nA-3fijA:
undetectable		 5j4nA-3fijA:
21.13