SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 5 ASP A 285
VAL A 275
SER A 277
GLN A 167
 None
 1.13A 1n2xB-3fipA:
undetectable		 1n2xB-3fipA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 8 ARG A 316
GLU A 269
GLN A 595
SER A 557
 None
 1.33A 1nx9A-3fipA:
undetectable		 1nx9A-3fipA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 8 ARG A 316
GLU A 269
GLN A 595
SER A 557
 None
 1.34A 1nx9B-3fipA:
undetectable		 1nx9B-3fipA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 8 ARG A 316
GLU A 269
GLN A 595
SER A 557
 None
 1.31A 1nx9C-3fipA:
undetectable		 1nx9C-3fipA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 8 ARG A 316
GLU A 269
GLN A 595
SER A 557
 None
 1.33A 1nx9D-3fipA:
undetectable		 1nx9D-3fipA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		3 / 3 TYR A 348
ARG A 281
GLN A 278
 None
 0.79A 1tw4A-3fipA:
2.8		 1tw4A-3fipA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 6 ARG A 273
ASN A 599
PRO A 289
ALA A 290
 None
 1.29A 2ejfB-3fipA:
undetectable		 2ejfB-3fipA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		3 / 3 ASN A 153
TYR A 284
SER A 630
 None
 0.94A 2gvcE-3fipA:
undetectable		 2gvcE-3fipA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 7 LYS A 534
ARG A 316
ASN A 314
ALA A 272
 None
 1.34A 3frqB-3fipA:
undetectable		 3frqB-3fipA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 4 GLY A 374
TYR A 373
GLY A 388
ASP A 402
 None
 0.73A 3kl3A-3fipA:
undetectable		 3kl3A-3fipA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		3 / 3 TYR A 448
TYR A 382
GLU A 467
 None
 0.74A 3pfgA-3fipA:
1.7		 3pfgA-3fipA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		3 / 3 GLN A 191
PHE A 168
TYR A 170
 None
 0.79A 3ucjB-3fipA:
undetectable		 3ucjB-3fipA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		3 / 3 GLN A 191
PHE A 168
TYR A 170
 None
 0.81A 3ucjA-3fipA:
undetectable		 3ucjA-3fipA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		5 / 12 GLY A 360
VAL A 341
PHE A 357
TYR A 382
ALA A 384
 None
 1.08A 5n0oA-3fipA:
undetectable		 5n0oA-3fipA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		5 / 12 GLY A 360
VAL A 341
PHE A 357
TYR A 382
ALA A 384
 None
 1.07A 5n0rA-3fipA:
undetectable		 5n0rA-3fipA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		5 / 12 GLY A 360
VAL A 341
PHE A 357
TYR A 382
ALA A 384
 None
 1.06A 5n0sA-3fipA:
undetectable		 5n0sA-3fipA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		5 / 12 GLY A 360
VAL A 341
PHE A 357
TYR A 382
ALA A 384
 None
 1.09A 5n0tA-3fipA:
undetectable		 5n0tA-3fipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		5 / 12 GLY A 360
VAL A 341
PHE A 357
TYR A 382
ALA A 384
 None
 1.07A 5n0wA-3fipA:
undetectable		 5n0wA-3fipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		5 / 12 GLY A 360
VAL A 341
PHE A 357
TYR A 382
ALA A 384
 None
 1.07A 5n0wB-3fipA:
undetectable		 5n0wB-3fipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		5 / 12 GLY A 360
VAL A 341
PHE A 357
TYR A 382
ALA A 384
 None
 1.07A 5n4iA-3fipA:
undetectable		 5n4iA-3fipA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 4 THR A 324
ASP A 323
ARG A 305
LEU A 306
 None
 1.19A 5tdmA-3fipA:
undetectable		 5tdmA-3fipA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3fip OUTER MEMBRANE USHER
PROTEIN PAPC
(Escherichia
coli) 		4 / 8 SER A 624
GLY A 568
SER A 553
ASN A 271
 None
 1.09A 6giqL-3fipA:
undetectable
6giqP-3fipA:
undetectable
6giqT-3fipA:
undetectable		 6giqL-3fipA:
22.98
6giqP-3fipA:
18.66
6giqT-3fipA:
9.18