SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fj1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 5 LEU A  95
LEU A  60
LEU A 309
GLY A 162
 None
 0.82A 1a4lC-3fj1A:
undetectable		 1a4lC-3fj1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 11 LEU A 182
ILE A  15
PRO A  16
ILE A 312
TYR A  59
 None
 1.05A 1dyrA-3fj1A:
undetectable		 1dyrA-3fj1A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 12 TYR A  59
GLY A 162
VAL A  19
LEU A  23
ALA A 178
 None
 1.29A 1e3vA-3fj1A:
undetectable		 1e3vA-3fj1A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 11 VAL A  48
VAL A 134
SER A 135
LEU A 131
ALA A 113
 None
 1.15A 1eqgB-3fj1A:
1.1		 1eqgB-3fj1A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 12 HIS A 303
ALA A 304
GLY A 302
GLU A 266
ARG A 289
 None
 1.31A 1mj2A-3fj1A:
undetectable
1mj2B-3fj1A:
undetectable		 1mj2A-3fj1A:
16.61
1mj2B-3fj1A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 4 LEU A 123
VAL A 121
CYH A 120
ALA A 118
 None
 1.20A 1mz9E-3fj1A:
undetectable		 1mz9E-3fj1A:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 4 THR A 185
LEU A 182
VAL A  19
LEU A  22
 None
 0.98A 1mz9D-3fj1A:
undetectable		 1mz9D-3fj1A:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 11 VAL A 313
ILE A  15
LEU A 186
LEU A 182
TYR A  59
 None
 1.16A 2a15A-3fj1A:
undetectable		 2a15A-3fj1A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 11 ALA A 159
ALA A 161
LEU A 123
SER A  53
VAL A  97
 None
 1.12A 2bxeB-3fj1A:
undetectable		 2bxeB-3fj1A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 12 GLY A 302
GLY A 174
LEU A 175
ASN A 181
ALA A 177
 None
 0.95A 3av6A-3fj1A:
undetectable		 3av6A-3fj1A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 GLU A 320
ASP A  13
ASP A 193
 None
 0.68A 3jb2A-3fj1A:
undetectable		 3jb2A-3fj1A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 7 ILE A 141
LEU A  22
THR A 138
ILE A 139
 None
 0.97A 3p50A-3fj1A:
undetectable		 3p50A-3fj1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 7 ILE A 141
LEU A  22
THR A 138
ILE A 139
 None
 0.95A 3p50B-3fj1A:
undetectable		 3p50B-3fj1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 7 ILE A 141
LEU A  22
THR A 138
ILE A 139
 None
 0.96A 3p50C-3fj1A:
undetectable		 3p50C-3fj1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 7 ILE A 141
LEU A  22
THR A 138
ILE A 139
 None
 0.96A 3p50D-3fj1A:
undetectable		 3p50D-3fj1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 7 ILE A 141
LEU A  22
THR A 138
ILE A 139
 None
 0.92A 3p50E-3fj1A:
undetectable		 3p50E-3fj1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 12 VAL A 121
LEU A  95
VAL A  30
ALA A  34
LEU A  37
 None
 1.07A 3pghD-3fj1A:
1.8		 3pghD-3fj1A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 10 ALA A 281
VAL A 256
ILE A 249
ALA A 273
VAL A 283
 None
 1.04A 3t3cB-3fj1A:
undetectable		 3t3cB-3fj1A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 12 LEU A  23
VAL A  19
ALA A 188
LEU A  60
THR A 306
 None
 1.39A 4iarA-3fj1A:
undetectable		 4iarA-3fj1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 9 SER A 239
ALA A 273
ALA A 293
GLY A 211
ALA A 260
 None
 1.04A 5d0xK-3fj1A:
undetectable
5d0xL-3fj1A:
undetectable		 5d0xK-3fj1A:
22.25
5d0xL-3fj1A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 9 SER A 239
ALA A 273
ALA A 293
GLY A 211
ALA A 260
 None
 1.02A 5d0xY-3fj1A:
undetectable
5d0xZ-3fj1A:
undetectable		 5d0xY-3fj1A:
22.25
5d0xZ-3fj1A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 9 GLY A 258
THR A 286
LEU A 269
ASN A 220
LEU A 311
 None
 1.24A 5fhzB-3fj1A:
undetectable		 5fhzB-3fj1A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 ALA A 178
ASN A 181
LEU A 182
 None
 0.27A 5i1nC-3fj1A:
undetectable		 5i1nC-3fj1A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 ALA A 178
ASN A 181
LEU A 182
 None
 0.18A 5i1oC-3fj1A:
undetectable		 5i1oC-3fj1A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 ALA A 178
ASN A 181
LEU A 182
 None
 0.50A 5i1oA-3fj1A:
undetectable		 5i1oA-3fj1A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 ALA A 178
ASN A 181
LEU A 182
 None
 0.29A 5i1pA-3fj1A:
undetectable		 5i1pA-3fj1A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		3 / 3 ALA A 178
ASN A 181
LEU A 182
 None
 0.25A 5i1pD-3fj1A:
undetectable		 5i1pD-3fj1A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 12 VAL A 121
LEU A  95
VAL A  30
ALA A  34
LEU A  37
 None
 1.11A 5ikrB-3fj1A:
1.6		 5ikrB-3fj1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		4 / 8 SER A 301
ASP A 307
PRO A 308
TYR A  59
 None
 1.13A 5l1fA-3fj1A:
undetectable
5l1fB-3fj1A:
2.3		 5l1fA-3fj1A:
18.09
5l1fB-3fj1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE
(Ruegeria
pomeroyi) 		5 / 10 SER A 135
GLY A 133
ALA A 127
GLY A 101
LEU A 186
 None
 1.26A 6hqbA-3fj1A:
undetectable
6hqbJ-3fj1A:
undetectable		 6hqbA-3fj1A:
12.80
6hqbJ-3fj1A:
8.04