SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQU_A_EQIA329_0
(PROTEIN (ESTRADIOL
17
BETA-DEHYDROGENASE
1))		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 10 SER A 270
VAL A 271
LEU A 224
GLY A 298
GLU A 329
 None
None
None
None
MUC  A 383 (-3.2A)
 1.42A 1equA-3fj4A:
undetectable		 1equA-3fj4A:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		6 / 11 GLY A  51
ALA A 113
ASP A 116
ILE A  14
VAL A  77
ILE A 110
 None
 1.43A 1ohrA-3fj4A:
undetectable		 1ohrA-3fj4A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 5 LEU A 129
ALA A 117
LEU A 115
SER A 112
 None
 1.12A 1tt6B-3fj4A:
undetectable		 1tt6B-3fj4A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 109
GLY A 310
LEU A 114
LEU A 115
LEU A  96
 None
 1.04A 2nyuA-3fj4A:
undetectable		 2nyuA-3fj4A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 109
GLY A 310
LEU A 114
LEU A 115
LEU A  96
 None
 0.99A 2nyuB-3fj4A:
2.3		 2nyuB-3fj4A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 5 LEU A  41
GLY A  51
ILE A  73
ILE A  11
 None
 0.83A 2q9rA-3fj4A:
undetectable		 2q9rA-3fj4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 11 LEU A  41
LEU A 360
LEU A  81
ILE A 276
ILE A  89
 None
 1.12A 2uxoB-3fj4A:
undetectable		 2uxoB-3fj4A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 SER A 112
LEU A 330
ILE A 276
ALA A 317
THR A 320
 None
 1.23A 2v0mC-3fj4A:
undetectable		 2v0mC-3fj4A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 11 SER A 108
LEU A 330
ILE A 276
ALA A 317
LEU A 360
 None
 1.36A 2v0mD-3fj4A:
undetectable		 2v0mD-3fj4A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 11 SER A 112
LEU A 330
ILE A 276
ALA A 317
THR A 320
 None
 1.19A 2v0mD-3fj4A:
undetectable		 2v0mD-3fj4A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 ILE A 340
LEU A  18
ASP A 339
GLY A 308
ILE A 309
 None
 1.08A 2ycjA-3fj4A:
6.3		 2ycjA-3fj4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 7 GLY A 109
SER A 112
ALA A 313
ILE A  69
 None
 0.79A 3a2qA-3fj4A:
undetectable		 3a2qA-3fj4A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		3 / 3 LEU A 321
VAL A 354
ARG A 135
 None
 0.74A 3b0wB-3fj4A:
undetectable		 3b0wB-3fj4A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 LEU A  50
GLY A  51
GLY A 109
SER A 108
LEU A  38
 None
 0.98A 3cjtO-3fj4A:
2.2		 3cjtO-3fj4A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		6 / 12 GLY A  51
ALA A 113
ASP A 116
ILE A  14
VAL A  77
ILE A 110
 None
 1.49A 3el1B-3fj4A:
undetectable		 3el1B-3fj4A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 THR A 328
VAL A 140
PHE A 318
ILE A 276
THR A  54
 None
 1.40A 3em0A-3fj4A:
0.2		 3em0A-3fj4A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 ILE A 222
GLY A 218
GLY A 219
ILE A 216
PRO A 247
 None
 0.89A 3jayA-3fj4A:
undetectable		 3jayA-3fj4A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 LEU A 369
ARG A  40
GLY A 310
THR A 311
LEU A 364
 None
 1.02A 3okxB-3fj4A:
undetectable		 3okxB-3fj4A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 ILE A 276
GLY A 310
THR A 311
GLU A  52
THR A  54
 None
 1.18A 3r75A-3fj4A:
undetectable		 3r75A-3fj4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 ILE A 276
GLY A 310
THR A 311
GLU A  52
THR A  54
 None
 1.19A 3r75B-3fj4A:
undetectable		 3r75B-3fj4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 11 ILE A 276
GLY A 310
THR A 311
GLU A  52
THR A  54
 None
 1.17A 3r76A-3fj4A:
undetectable		 3r76A-3fj4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 11 ILE A 276
GLY A 310
THR A 311
GLU A  52
THR A  54
 None
 1.17A 3r76B-3fj4A:
undetectable		 3r76B-3fj4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 7 LEU A 224
VAL A 271
LEU A 263
ASP A 251
 None
None
None
MG  A1001 ( 3.3A)
 0.88A 3rgfA-3fj4A:
undetectable		 3rgfA-3fj4A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 6 PHE A  76
ARG A  75
LEU A  80
PRO A  79
 None
 1.28A 3vlnA-3fj4A:
undetectable		 3vlnA-3fj4A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 8 SER A  53
ARG A 374
ILE A  69
GLU A  52
 None
 1.18A 4cx7A-3fj4A:
undetectable
4cx7B-3fj4A:
undetectable		 4cx7A-3fj4A:
22.50
4cx7B-3fj4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 8 SER A  53
ARG A 374
ILE A  69
GLU A  52
 None
 1.21A 4cx7C-3fj4A:
undetectable
4cx7D-3fj4A:
0.0		 4cx7C-3fj4A:
22.50
4cx7D-3fj4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 280
THR A 285
LEU A 286
SER A 112
VAL A 126
 None
 1.23A 4f84A-3fj4A:
undetectable		 4f84A-3fj4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 10 GLU A  48
ALA A 113
ILE A  11
ALA A  86
ILE A   8
 None
 1.04A 4lbgA-3fj4A:
2.7		 4lbgA-3fj4A:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 4 HIS A 165
ALA A 141
VAL A 140
GLU A 329
 None
None
None
MUC  A 383 (-3.2A)
 1.08A 4n6pA-3fj4A:
undetectable		 4n6pA-3fj4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 9 ALA A 113
ILE A 309
GLY A 310
ILE A 276
ILE A  73
 None
 1.12A 4nptA-3fj4A:
undetectable		 4nptA-3fj4A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 307
GLY A 308
LEU A 312
LEU A 330
GLY A 332
 None
 0.86A 4o33A-3fj4A:
undetectable		 4o33A-3fj4A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 307
GLY A 308
LEU A 312
LEU A 330
GLY A 332
 None
 0.89A 4o3fA-3fj4A:
undetectable		 4o3fA-3fj4A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 7 THR A 143
HIS A  24
LEU A  26
ASN A 202
 MUC  A 383 (-3.0A)
MUC  A 383 (-4.1A)
None
MUC  A 383 ( 4.0A)
 1.09A 4pfjA-3fj4A:
undetectable		 4pfjA-3fj4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 7 THR A  54
GLU A  52
GLY A 332
GLY A 307
 None
 0.68A 4rdxA-3fj4A:
undetectable		 4rdxA-3fj4A:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 LEU A 130
LEU A 321
THR A 303
ALA A 289
ILE A 276
 None
None
MUC  A 383 (-4.6A)
None
None
 1.16A 4x1kD-3fj4A:
undetectable		 4x1kD-3fj4A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 9 THR A  20
ILE A  21
GLY A 332
THR A 303
LEU A  26
 None
None
None
MUC  A 383 (-4.6A)
None
 0.92A 4ze0A-3fj4A:
undetectable		 4ze0A-3fj4A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		3 / 3 ASN A 233
ALA A 235
ARG A 239
 None
 0.60A 5cvtB-3fj4A:
3.9		 5cvtB-3fj4A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 5 ARG A  22
ILE A  21
GLY A 332
LEU A 336
 None
 0.85A 5dzki-3fj4A:
3.4
5dzkj-3fj4A:
2.0
5dzkx-3fj4A:
undetectable		 5dzki-3fj4A:
21.37
5dzkj-3fj4A:
21.37
5dzkx-3fj4A:
2.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 4 THR A  20
LEU A 335
HIS A  24
GLY A 332
 None
None
MUC  A 383 (-4.1A)
None
 1.28A 5gwyA-3fj4A:
undetectable		 5gwyA-3fj4A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 8 ILE A  21
GLY A 332
THR A 303
LEU A  26
 None
None
MUC  A 383 (-4.6A)
None
 0.78A 5hs1A-3fj4A:
undetectable		 5hs1A-3fj4A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 ILE A 276
GLY A 280
ASN A 279
ALA A 289
ILE A  89
 None
 1.15A 5igyA-3fj4A:
undetectable		 5igyA-3fj4A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		5 / 12 ILE A 222
ARG A 198
PRO A 247
GLY A 219
GLY A 221
 None
 1.13A 5l6eA-3fj4A:
undetectable		 5l6eA-3fj4A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 3fj4 MUCONATE
CYCLOISOMERASE
(Pseudomonas
protegens) 		4 / 6 GLN A 157
LEU A 191
SER A 194
PHE A 168
 None
 1.21A 6ekuA-3fj4A:
undetectable		 6ekuA-3fj4A:
18.98