SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fjo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 10 GLY A 522
PHE A 520
LEU A 559
THR A 540
LEU A 568
 None
 0.95A 1a8uA-3fjoA:
2.9		 1a8uA-3fjoA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 10 GLY A 522
PHE A 520
LEU A 559
THR A 540
LEU A 568
 None
 1.00A 1a8uB-3fjoA:
3.2		 1a8uB-3fjoA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 7 TYR A  75
ASP A 193
GLU A 194
PHE A 150
 None
 1.48A 1b2iA-3fjoA:
undetectable		 1b2iA-3fjoA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 7 THR A  71
THR A 117
GLY A 153
TYR A 157
 FMN  A 751 (-3.6A)
FMN  A 751 (-3.9A)
FMN  A 751 (-3.2A)
FMN  A 751 (-3.7A)
 0.70A 1bu5A-3fjoA:
17.8		 1bu5A-3fjoA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 8 THR A  71
THR A 117
GLY A 153
TYR A 157
 FMN  A 751 (-3.6A)
FMN  A 751 (-3.9A)
FMN  A 751 (-3.2A)
FMN  A 751 (-3.7A)
 0.73A 1bu5B-3fjoA:
17.9		 1bu5B-3fjoA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		4 / 4 ALA A 560
ARG A 556
GLN A 561
GLU A 557
 None
 1.39A 1lquB-3fjoA:
undetectable		 1lquB-3fjoA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 11 GLU A 120
GLY A 121
GLU A 184
LEU A 182
GLU A 168
 None
 1.35A 1mjqA-3fjoA:
undetectable
1mjqB-3fjoA:
undetectable		 1mjqA-3fjoA:
11.25
1mjqB-3fjoA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 7 GLU A 558
LEU A 272
TYR A 553
ILE A 521
 None
 1.03A 1tuvA-3fjoA:
undetectable		 1tuvA-3fjoA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 ALA A 373
LEU A 382
GLU A 378
GLN A 412
PRO A 361
 None
 1.33A 1u72A-3fjoA:
undetectable		 1u72A-3fjoA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 7 ALA A 301
ILE A 292
ASP A 257
PHE A 256
 None
 0.85A 1upfB-3fjoA:
2.3		 1upfB-3fjoA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		4 / 6 ALA A 164
TYR A 147
ILE A 113
LEU A 182
 None
 0.90A 1xvaA-3fjoA:
3.4
1xvaB-3fjoA:
3.2		 1xvaA-3fjoA:
19.46
1xvaB-3fjoA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 GLY A 610
TYR A 436
VAL A 511
ALA A 616
ASP A 611
 None
FAD  A 750 (-4.3A)
None
None
None
 1.15A 2avdB-3fjoA:
3.1		 2avdB-3fjoA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 LEU A 542
GLY A 516
CYH A 452
ALA A 518
ALA A 439
 None
None
None
FAD  A 750 ( 4.2A)
None
 1.10A 2br4A-3fjoA:
4.4		 2br4A-3fjoA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		3 / 3 ILE A 203
ILE A 110
LEU A 152
 None
None
FMN  A 751 (-4.5A)
 0.52A 2prgA-3fjoA:
undetectable		 2prgA-3fjoA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 ALA A 320
LEU A 351
ILE A 407
LEU A 428
PRO A 429
 None
 1.20A 2qk8A-3fjoA:
undetectable		 2qk8A-3fjoA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 6 VAL A 493
VAL A 300
PHE A 256
ARG A 434
 None
None
None
FAD  A 750 (-3.9A)
 1.15A 3bjwF-3fjoA:
undetectable		 3bjwF-3fjoA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 GLY A 151
THR A 192
SER A 112
ALA A 167
ILE A 115
 None
 1.18A 3id6C-3fjoA:
5.4		 3id6C-3fjoA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 ALA A  51
PHE A 101
LEU A 104
ILE A 113
LEU A 171
LEU A 145
 None
 1.44A 3k2hA-3fjoA:
3.0		 3k2hA-3fjoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 LEU A 272
GLY A 516
ALA A 518
ILE A 438
GLY A 522
ILE A 524
 None
None
FAD  A 750 ( 4.2A)
None
None
None
 1.38A 3k4vA-3fjoA:
undetectable		 3k4vA-3fjoA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 LEU A 272
GLY A 516
ALA A 518
ILE A 438
GLY A 522
ILE A 524
 None
None
FAD  A 750 ( 4.2A)
None
None
None
 1.39A 3k4vB-3fjoA:
undetectable		 3k4vB-3fjoA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 GLY A 514
GLY A 545
VAL A 511
ALA A 518
SER A 576
 None
None
None
FAD  A 750 ( 4.2A)
None
 1.20A 3mteA-3fjoA:
undetectable		 3mteA-3fjoA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 LEU A 272
GLY A 516
ALA A 518
ILE A 438
GLY A 522
ILE A 524
 None
None
FAD  A 750 ( 4.2A)
None
None
None
 1.39A 3ndtA-3fjoA:
undetectable		 3ndtA-3fjoA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 10 LEU A 542
ALA A 518
PHE A 520
GLY A 522
ILE A 524
 None
FAD  A 750 ( 4.2A)
None
None
None
 1.01A 3qpsA-3fjoA:
undetectable		 3qpsA-3fjoA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 5 PRO A 429
ASP A 356
ILE A 407
VAL A 311
 None
 1.21A 4hytA-3fjoA:
undetectable		 4hytA-3fjoA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		4 / 6 GLU A 295
ARG A 293
GLU A 526
SER A 441
 None
 1.17A 4kr3A-3fjoA:
3.9		 4kr3A-3fjoA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		3 / 3 ILE A 134
MET A 149
ARG A 178
 None
 0.87A 4lnwA-3fjoA:
undetectable		 4lnwA-3fjoA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 LYS A 643
ASN A 621
ASP A 640
 None
 0.82A 4o1eA-3fjoA:
undetectable		 4o1eA-3fjoA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		4 / 4 LEU A 397
VAL A 401
GLU A 402
ARG A 404
 None
None
None
FAD  A 750 (-3.7A)
 1.33A 4ww7A-3fjoA:
undetectable		 4ww7A-3fjoA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		3 / 3 THR A 231
HIS A 423
LEU A 328
 None
 0.76A 5axdC-3fjoA:
undetectable		 5axdC-3fjoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 VAL A 324
ASP A 323
LEU A 328
GLY A 315
LEU A 318
 None
 1.00A 5m5cB-3fjoA:
3.2		 5m5cB-3fjoA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 VAL A 324
ASP A 323
LEU A 328
GLY A 315
LEU A 318
 None
 1.00A 5m5cE-3fjoA:
3.9		 5m5cE-3fjoA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		4 / 4 TYR A 367
SER A 387
GLN A 379
THR A 216
 None
 1.39A 5n0tB-3fjoA:
0.9		 5n0tB-3fjoA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		4 / 8 LEU A 589
ALA A 604
VAL A 585
TYR A 651
 None
 0.97A 5nu7A-3fjoA:
undetectable		 5nu7A-3fjoA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.61A 5qgjA-3fjoA:
undetectable		 5qgjA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.61A 5qglA-3fjoA:
undetectable		 5qglA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.63A 5qgmA-3fjoA:
undetectable		 5qgmA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.65A 5qgnA-3fjoA:
undetectable		 5qgnA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.58A 5qguA-3fjoA:
undetectable		 5qguA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.59A 5qgvA-3fjoA:
undetectable		 5qgvA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.58A 5qgwA-3fjoA:
undetectable		 5qgwA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.59A 5qgxA-3fjoA:
undetectable		 5qgxA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.60A 5qgyA-3fjoA:
undetectable		 5qgyA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.59A 5qgzA-3fjoA:
undetectable		 5qgzA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.58A 5qh0A-3fjoA:
undetectable		 5qh0A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.60A 5qh1A-3fjoA:
undetectable		 5qh1A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.58A 5qh2A-3fjoA:
undetectable		 5qh2A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.60A 5qh3A-3fjoA:
undetectable		 5qh3A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.61A 5qh4A-3fjoA:
undetectable		 5qh4A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.63A 5qh5A-3fjoA:
undetectable		 5qh5A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.59A 5qh6A-3fjoA:
undetectable		 5qh6A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.61A 5qh7A-3fjoA:
undetectable		 5qh7A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.58A 5qh9A-3fjoA:
undetectable		 5qh9A-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.55A 5qhaA-3fjoA:
undetectable		 5qhaA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.59A 5qhcA-3fjoA:
undetectable		 5qhcA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.58A 5qheA-3fjoA:
undetectable		 5qheA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.59A 5qhfA-3fjoA:
undetectable		 5qhfA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.64A 5qhgA-3fjoA:
undetectable		 5qhgA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		3 / 3 VAL A 608
VAL A 511
GLN A 586
 None
 0.60A 5qhhA-3fjoA:
undetectable		 5qhhA-3fjoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 9 SER A 437
THR A 515
GLY A 516
ALA A 518
CYH A 609
GLY A 610
 FAD  A 750 (-3.7A)
FAD  A 750 ( 3.9A)
None
FAD  A 750 ( 4.2A)
None
None
 0.55A 5vw4A-3fjoA:
29.6		 5vw4A-3fjoA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 8 SER A 437
THR A 515
GLY A 516
CYH A 609
GLY A 610
 FAD  A 750 (-3.7A)
FAD  A 750 ( 3.9A)
None
None
None
 0.56A 5vw5A-3fjoA:
29.4		 5vw5A-3fjoA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 8 SER A 437
THR A 515
GLY A 516
ALA A 518
CYH A 609
GLY A 610
 FAD  A 750 (-3.7A)
FAD  A 750 ( 3.9A)
None
FAD  A 750 ( 4.2A)
None
None
 0.58A 5vw9A-3fjoA:
29.6		 5vw9A-3fjoA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 8 GLU A 557
HIS A 282
GLN A 561
LEU A 559
 None
 0.93A 5w3jB-3fjoA:
undetectable		 5w3jB-3fjoA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 6 PRO A 513
GLY A 545
LEU A 588
VAL A 511
 None
 0.91A 5x80A-3fjoA:
undetectable
5x80B-3fjoA:
2.1		 5x80A-3fjoA:
16.40
5x80B-3fjoA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 VAL A 324
ASP A 323
LEU A 328
GLY A 315
LEU A 318
 None
 1.10A 6b0lB-3fjoA:
undetectable		 6b0lB-3fjoA:
8.68