SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		5 / 12 HIS A 196
ILE A 247
ILE A 243
ARG A 127
GLU A 270
 ZN  A 999 (-3.2A)
None
None
ACT  A 515 (-3.4A)
ACT  A 515 (-4.3A)
 1.38A 1ki7B-3fjuA:
2.3		 1ki7B-3fjuA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 7 SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
ACT  A 515 (-4.3A)
 1.19A 2c8aA-3fjuA:
undetectable		 2c8aA-3fjuA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		5 / 7 GLY A 278
SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
None
ACT  A 515 (-4.3A)
 1.29A 2c8aB-3fjuA:
undetectable		 2c8aB-3fjuA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 8 ILE A 193
SER A 194
ASP A  65
SER A  78
 None
 0.84A 2cdqA-3fjuA:
undetectable		 2cdqA-3fjuA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 5 SER A 197
LEU A 280
GLY A 278
ARG A 124
 None
 0.98A 2j2pA-3fjuA:
undetectable
2j2pB-3fjuA:
undetectable		 2j2pA-3fjuA:
18.99
2j2pB-3fjuA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 6 ARG A 124
SER A 197
LEU A 280
GLY A 278
 None
 1.03A 2j2pD-3fjuA:
undetectable
2j2pF-3fjuA:
undetectable		 2j2pD-3fjuA:
18.99
2j2pF-3fjuA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		3 / 3 GLU A 270
HIS A  69
GLU A  72
 ACT  A 515 (-4.3A)
ZN  A 999 ( 3.1A)
ZN  A 999 (-2.1A)
 0.75A 2x45B-3fjuA:
undetectable		 2x45B-3fjuA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		3 / 3 GLU A 270
HIS A  69
GLU A  72
 ACT  A 515 (-4.3A)
ZN  A 999 ( 3.1A)
ZN  A 999 (-2.1A)
 0.77A 2x45C-3fjuA:
undetectable		 2x45C-3fjuA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		5 / 11 ALA A 229
LEU A 222
ILE A 193
PHE A 269
THR A 228
 None
 1.24A 3jw5A-3fjuA:
undetectable		 3jw5A-3fjuA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 5 THR A 129
GLY A 115
PRO A 113
ASN A 112
 None
 0.87A 3u8qA-3fjuA:
undetectable		 3u8qA-3fjuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3fju CARBOXYPEPTIDASE A
INHIBITOR
(Ascaris
suum) 		3 / 3 ASN B  14
GLU B  16
ARG B   4
 None
 0.88A 3wxoA-3fjuB:
undetectable		 3wxoA-3fjuB:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 6 THR A 129
GLY A 115
ASN A 112
GLY A  44
 None
 0.86A 4fjpA-3fjuA:
undetectable		 4fjpA-3fjuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 6 THR A 129
GLY A 115
PRO A 113
ASN A 112
 None
 0.86A 4fjpA-3fjuA:
undetectable		 4fjpA-3fjuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3fju CARBOXYPEPTIDASE A1
CARBOXYPEPTIDASE A
INHIBITOR
(Homo
sapiens;
Ascaris
suum) 		5 / 12 ILE B  57
ILE A 255
ASP A 256
GLY A 207
ILE A 243
 None
 1.20A 4o1eA-3fjuB:
undetectable		 4o1eA-3fjuB:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 5 LEU A 103
PHE A  96
ILE A 105
ILE A  86
 None
 1.07A 5dzk4-3fjuA:
undetectable
5dzkg-3fjuA:
undetectable
5dzkm-3fjuA:
undetectable
5dzkn-3fjuA:
undetectable		 5dzk4-3fjuA:
8.33
5dzkg-3fjuA:
20.55
5dzkm-3fjuA:
22.56
5dzkn-3fjuA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3fju CARBOXYPEPTIDASE A1
(Homo
sapiens) 		4 / 6 PHE A 269
LEU A 201
SER A 223
GLY A 241
 None
 1.12A 5o4yF-3fjuA:
undetectable		 5o4yF-3fjuA:
4.03