SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	3fjv	UNCHARACTERIZED NOVEL PROTEIN (Burkholderia pseudomallei)	5 / 12	LEU A 86 LEU A 116 ILE A 166 ILE A 180 ALA A 185	None	0.91A	2bxqA-3fjvA: 2.7	2bxqA-3fjvA: 16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_A_SNLA1001_1 (MINERALOCORTICOID RECEPTOR)	3fjv	UNCHARACTERIZED NOVEL PROTEIN (Burkholderia pseudomallei)	5 / 12	LEU A 43 LEU A 146 LEU A 116 LEU A 188 THR A 49	None	1.46A	2oaxA-3fjvA: undetectable	2oaxA-3fjvA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BA0_A_HAEA477_1 (MACROPHAGE METALLOELASTASE)	3fjv	UNCHARACTERIZED NOVEL PROTEIN (Burkholderia pseudomallei)	3 / 3	HIS A 55 GLU A 56 HIS A 22	None	0.83A	3ba0A-3fjvA: undetectable	3ba0A-3fjvA: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_D_MTXD615_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3fjv	UNCHARACTERIZED NOVEL PROTEIN (Burkholderia pseudomallei)	5 / 12	LEU A 158 ASP A 191 LEU A 86 ILE A 166 LEU A 42	None	1.06A	3hj3D-3fjvA: undetectable	3hj3D-3fjvA: 17.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BXQ_A_P1ZA2002_1","SERUM ALBUMIN","3fjv","UNCHARACTERIZED NOVEL PROTEIN","Burkholderia pseudomallei",5,"LEU A  86;LEU A 116;ILE A 166;ILE A 180;ALA A 185","None","0.91A","2bxqA-3fjvA:2.7","2bxqA-3fjvA:16.12"],["2OAX_A_SNLA1001_1","MINERALOCORTICOID RECEPTOR","3fjv","UNCHARACTERIZED NOVEL PROTEIN","Burkholderia pseudomallei",5,"LEU A  43;LEU A 146;LEU A 116;LEU A 188;THR A  49","None","1.46A","2oaxA-3fjvA:undetectable","2oaxA-3fjvA:20.24"],["3BA0_A_HAEA477_1","MACROPHAGE METALLOELASTASE","3fjv","UNCHARACTERIZED NOVEL PROTEIN","Burkholderia pseudomallei",3,"HIS A  55;GLU A  56;HIS A  22","None","0.83A","3ba0A-3fjvA:undetectable","3ba0A-3fjvA:18.35"],["3HJ3_D_MTXD615_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3fjv","UNCHARACTERIZED NOVEL PROTEIN","Burkholderia pseudomallei",5,"LEU A 158;ASP A 191;LEU A  86;ILE A 166;LEU A  42","None","1.06A","3hj3D-3fjvA:undetectable","3hj3D-3fjvA:17.18"]]