SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fjy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_0
(PROTEIN (METHIONINE
REPRESSOR))		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 9 ARG A  76
GLU A  77
ALA A  12
HIS A  70
LEU A  64
 None
 1.45A 1mj2A-3fjyA:
undetectable		 1mj2A-3fjyA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_0
(METHIONINE REPRESSOR)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 9 ARG A  76
GLU A  77
ALA A  12
HIS A  70
LEU A  64
 None
 1.45A 1mjoA-3fjyA:
undetectable		 1mjoA-3fjyA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_1
(METHIONINE REPRESSOR)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 9 ARG A  76
GLU A  77
ALA A  12
HIS A  70
LEU A  64
 None
 1.45A 1mjoB-3fjyA:
undetectable		 1mjoB-3fjyA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_0
(METHIONINE REPRESSOR)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 9 ARG A  76
GLU A  77
ALA A  12
HIS A  70
LEU A  64
 None
 1.45A 1mjoC-3fjyA:
undetectable		 1mjoC-3fjyA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 4 GLY A  14
VAL A  16
TRP A 122
GLY A  89
 None
 1.26A 1ng8A-3fjyA:
undetectable		 1ng8A-3fjyA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 4 GLY A  14
VAL A  16
TRP A 122
GLY A  89
 None
 1.26A 1ng8B-3fjyA:
undetectable		 1ng8B-3fjyA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 7 VAL A 156
VAL A  16
TYR A  91
CYH A  93
 None
 1.29A 1t46A-3fjyA:
undetectable		 1t46A-3fjyA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 THR A 248
ALA A 297
ALA A 197
GLY A 335
THR A 336
 None
 1.11A 2f16H-3fjyA:
undetectable
2f16I-3fjyA:
undetectable		 2f16H-3fjyA:
21.67
2f16I-3fjyA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 THR A 248
ALA A 297
ALA A 197
GLY A 335
THR A 336
 None
 1.12A 2f16V-3fjyA:
undetectable
2f16W-3fjyA:
undetectable		 2f16V-3fjyA:
21.67
2f16W-3fjyA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 6 SER A 128
ASP A 131
ASP A 130
GLU A 294
 None
 1.22A 2j2pE-3fjyA:
undetectable
2j2pF-3fjyA:
undetectable		 2j2pE-3fjyA:
17.80
2j2pF-3fjyA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 7 ILE A 326
LEU A 325
GLY A 306
ARG A 195
 None
 0.76A 2wd9A-3fjyA:
undetectable		 2wd9A-3fjyA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 8 ILE A 326
LEU A 325
GLY A 306
ARG A 195
 None
 0.72A 2wd9B-3fjyA:
undetectable		 2wd9B-3fjyA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 THR A 248
ALA A 297
ALA A 197
GLY A 335
THR A 336
 None
 1.10A 3mg0V-3fjyA:
undetectable
3mg0W-3fjyA:
undetectable		 3mg0V-3fjyA:
21.67
3mg0W-3fjyA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 9 ARG A 283
ILE A 342
LEU A 325
LEU A 280
GLY A 306
 None
 1.23A 3nxuB-3fjyA:
undetectable		 3nxuB-3fjyA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 9 ARG A 283
ILE A 342
LEU A 325
LEU A 280
GLY A 307
 None
 1.36A 3nxuB-3fjyA:
undetectable		 3nxuB-3fjyA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 PHE A 139
CYH A 231
HIS A  72
 None
 1.24A 3u9fF-3fjyA:
undetectable		 3u9fF-3fjyA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 PHE A 139
CYH A 231
HIS A  72
 None
 1.22A 3u9fG-3fjyA:
undetectable		 3u9fG-3fjyA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 PHE A 139
CYH A 231
HIS A  72
 None
 1.14A 3u9fL-3fjyA:
undetectable		 3u9fL-3fjyA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 THR A 235
ASN A 233
GLU A 294
 None
 0.79A 3v4tA-3fjyA:
undetectable
3v4tC-3fjyA:
undetectable		 3v4tA-3fjyA:
22.07
3v4tC-3fjyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 ARG A 283
TRP A 279
ILE A 286
 None
 0.95A 4mwxA-3fjyA:
undetectable		 4mwxA-3fjyA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 ALA A 238
LEU A 237
MET A 308
LEU A 191
PRO A 234
 None
 0.97A 4xi3D-3fjyA:
undetectable		 4xi3D-3fjyA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 THR A 173
HIS A  72
LEU A  88
 None
 0.78A 5axdA-3fjyA:
undetectable		 5axdA-3fjyA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 THR A 173
HIS A  72
LEU A  88
 None
 0.74A 5axdC-3fjyA:
undetectable		 5axdC-3fjyA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 VAL A 304
ILE A 351
ILE A 298
LEU A 191
ILE A 286
 None
 0.99A 5mueA-3fjyA:
undetectable		 5mueA-3fjyA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 LEU A 229
LEU A 192
ARG A 195
THR A 336
ALA A 337
 None
 1.06A 5o96A-3fjyA:
undetectable
5o96B-3fjyA:
undetectable		 5o96A-3fjyA:
20.00
5o96B-3fjyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 ILE A  15
GLY A  14
GLY A  13
LEU A 165
SER A 166
 None
 0.89A 5twjD-3fjyA:
undetectable		 5twjD-3fjyA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 THR A 239
MET A 300
HIS A 301
 None
None
GOL  A 400 (-4.3A)
 0.91A 5uunA-3fjyA:
undetectable		 5uunA-3fjyA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 THR A 248
ALA A 297
ALA A 197
GLY A 335
THR A 336
 None
 1.07A 6hwdH-3fjyA:
undetectable
6hwdI-3fjyA:
undetectable		 6hwdH-3fjyA:
14.96
6hwdI-3fjyA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3fjy PROBABLE MUTT1
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 THR A 248
ALA A 297
ALA A 197
GLY A 335
THR A 336
 None
 1.07A 6hwdV-3fjyA:
undetectable		 6hwdV-3fjyA:
14.96