SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fku'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 3fku NEUTRALIZING
ANTIBODY F10
(Homo
sapiens) 		4 / 8 VAL X 248
ARG X 201
ALA X 157
GLU X 223
 None
 0.99A 1dmiA-3fkuX:
undetectable
1dmiB-3fkuX:
undetectable		 1dmiA-3fkuX:
20.00
1dmiB-3fkuX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 3fku NEUTRALIZING
ANTIBODY F10
(Homo
sapiens) 		5 / 12 ASP X 225
LYS X 245
PRO X 146
GLY X 241
LEU X 143
 None
 1.34A 2nv4B-3fkuX:
undetectable		 2nv4B-3fkuX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3fku NEUTRALIZING
ANTIBODY F10
(Homo
sapiens) 		5 / 12 LEU X  83
GLY X  49
ASN X  59
ASP X 232
VAL X 239
 None
 1.29A 2zznA-3fkuX:
undetectable		 2zznA-3fkuX:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3fku NEUTRALIZING
ANTIBODY F10
(Homo
sapiens) 		4 / 7 PHE X 240
GLY X 241
GLY X 243
ASN X 164
 None
 0.80A 5ybbB-3fkuX:
undetectable		 5ybbB-3fkuX:
20.08