SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3fl2 E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Homo
sapiens) 		4 / 7 PRO A 760
LEU A 766
GLY A 767
LEU A 748
 None
 0.87A 1ya4B-3fl2A:
undetectable		 1ya4B-3fl2A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3fl2 E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Homo
sapiens) 		3 / 3 ASN A 775
ASP A 687
ASN A 690
 None
 0.65A 4agaA-3fl2A:
undetectable		 4agaA-3fl2A:
15.67