SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fld'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 3fld PROTEIN TRAI
(Escherichia
coli) 		3 / 3 TRP A1542
ALA A1569
VAL A1572
 None
 0.96A 1av2C-3fldA:
undetectable
1av2D-3fldA:
undetectable		 1av2C-3fldA:
6.67
1av2D-3fldA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 3fld PROTEIN TRAI
(Escherichia
coli) 		3 / 3 ALA A1569
VAL A1572
TRP A1542
 None
 0.99A 2izqA-3fldA:
undetectable
2izqB-3fldA:
undetectable		 2izqA-3fldA:
6.67
2izqB-3fldA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3fld PROTEIN TRAI
(Escherichia
coli) 		3 / 3 SER A1558
GLY A1559
GLN A1589
 SO4  A1706 (-3.3A)
None
None
 0.63A 3v4tH-3fldA:
undetectable		 3v4tH-3fldA:
18.31