SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fm0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		5 / 12 HIS A  60
LEU A 120
VAL A 111
LEU A 101
THR A 100
 None
 1.02A 2aw1A-3fm0A:
undetectable		 2aw1A-3fm0A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		3 / 3 ASP A 325
SER A 303
ARG A  10
 None
 1.00A 3loqA-3fm0A:
undetectable		 3loqA-3fm0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		4 / 6 HIS A 155
SER A 199
ASP A 273
ASP A 257
 None
 1.38A 4blvA-3fm0A:
undetectable		 4blvA-3fm0A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		5 / 12 ASP A 273
GLY A 272
ASP A 305
ASP A 214
TRP A 198
 None
 1.18A 4pghB-3fm0A:
undetectable		 4pghB-3fm0A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 177
ASP A 171
 None
 0.64A 4rp8C-3fm0A:
undetectable		 4rp8C-3fm0A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		3 / 3 PRO A 160
LEU A 263
SER A 205
 None
 0.78A 5fsaB-3fm0A:
undetectable		 5fsaB-3fm0A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		4 / 7 LEU A   7
ALA A 329
ILE A 276
LEU A   5
 None
 0.91A 5te8C-3fm0A:
undetectable		 5te8C-3fm0A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 3fm0 PROTEIN CIAO1
(Homo
sapiens) 		4 / 6 SER A  70
ALA A  77
THR A  85
ALA A 121
 None
 1.15A 6ma6A-3fm0A:
undetectable		 6ma6A-3fm0A:
12.28