SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fm2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 3fm2 UNCHARACTERIZED
PROTEIN, DISTANTLY
RELATED TO A HEME
BINDING/DEGRADING
HEMS (PF05171)
FAMILY
(Trichormus
variabilis) 		5 / 12 LEU A  20
LEU A  18
LEU A 100
LEU A 119
LEU A   9
 None
 1.20A 3d90B-3fm2A:
undetectable		 3d90B-3fm2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3fm2 UNCHARACTERIZED
PROTEIN, DISTANTLY
RELATED TO A HEME
BINDING/DEGRADING
HEMS (PF05171)
FAMILY
(Trichormus
variabilis) 		3 / 3 PHE A  87
GLN A  92
PHE A   8
 None
 0.84A 3rv5A-3fm2A:
undetectable		 3rv5A-3fm2A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3fm2 UNCHARACTERIZED
PROTEIN, DISTANTLY
RELATED TO A HEME
BINDING/DEGRADING
HEMS (PF05171)
FAMILY
(Trichormus
variabilis) 		5 / 11 PHE A  99
LEU A  38
LEU A  15
GLY A  16
ALA A  11
 None
 1.31A 5fctA-3fm2A:
undetectable		 5fctA-3fm2A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3fm2 UNCHARACTERIZED
PROTEIN, DISTANTLY
RELATED TO A HEME
BINDING/DEGRADING
HEMS (PF05171)
FAMILY
(Trichormus
variabilis) 		4 / 5 LEU A  18
GLN A 101
PHE A  99
PHE A  58
 None
 1.43A 6nmpP-3fm2A:
undetectable
6nmpW-3fm2A:
undetectable		 6nmpP-3fm2A:
20.08
6nmpW-3fm2A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3fm2 UNCHARACTERIZED
PROTEIN, DISTANTLY
RELATED TO A HEME
BINDING/DEGRADING
HEMS (PF05171)
FAMILY
(Trichormus
variabilis) 		5 / 11 PHE A  99
LEU A  38
LEU A  15
GLY A  16
ALA A  11
 None
 1.32A 6r2eF-3fm2A:
undetectable		 6r2eF-3fm2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 3fm2 UNCHARACTERIZED
PROTEIN, DISTANTLY
RELATED TO A HEME
BINDING/DEGRADING
HEMS (PF05171)
FAMILY
(Trichormus
variabilis) 		5 / 12 PHE A  99
LEU A  38
LEU A  15
GLY A  16
ALA A  11
 None
 1.22A 6r2eH-3fm2A:
undetectable		 6r2eH-3fm2A:
19.86