SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fmp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		4 / 7 LEU B 103
GLN B 102
PHE B 188
PHE B  94
 None
 1.06A 2dysP-3fmpB:
undetectable
2dysW-3fmpB:
undetectable		 2dysP-3fmpB:
20.04
2dysW-3fmpB:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		4 / 6 LEU B 103
GLN B 102
PHE B 188
PHE B  94
 None
 1.10A 2einP-3fmpB:
undetectable
2einW-3fmpB:
undetectable		 2einP-3fmpB:
20.04
2einW-3fmpB:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		5 / 12 ILE B 295
ALA B 122
GLN B 119
ASN B  73
ALA B 147
 None
None
ADP  B 480 (-3.3A)
None
None
 1.11A 3dzyA-3fmpB:
undetectable		 3dzyA-3fmpB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		4 / 7 VAL B 181
ILE B 182
LEU B  99
LEU B 103
 None
 1.03A 4l1wA-3fmpB:
undetectable		 4l1wA-3fmpB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		5 / 11 LEU B  97
LEU B  99
LEU B 127
ALA B 146
LEU B 150
 None
None
None
ADP  B 480 (-3.4A)
None
 1.04A 4wg0B-3fmpB:
undetectable
4wg0C-3fmpB:
undetectable
4wg0D-3fmpB:
undetectable		 4wg0B-3fmpB:
2.88
4wg0C-3fmpB:
2.88
4wg0D-3fmpB:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		5 / 11 LEU B  97
LEU B  99
LEU B 127
ALA B 146
LEU B 150
 None
None
None
ADP  B 480 (-3.4A)
None
 1.04A 4wg0D-3fmpB:
undetectable
4wg0E-3fmpB:
undetectable
4wg0F-3fmpB:
undetectable		 4wg0D-3fmpB:
2.88
4wg0E-3fmpB:
2.88
4wg0F-3fmpB:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		5 / 11 LEU B  97
LEU B  99
LEU B 127
ALA B 146
LEU B 150
 None
None
None
ADP  B 480 (-3.4A)
None
 1.06A 4wg0F-3fmpB:
undetectable
4wg0G-3fmpB:
undetectable
4wg0H-3fmpB:
undetectable		 4wg0F-3fmpB:
2.88
4wg0G-3fmpB:
2.88
4wg0H-3fmpB:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		5 / 11 ALA B 146
LEU B 150
LEU B 127
LEU B  97
LEU B  99
 ADP  B 480 (-3.4A)
None
None
None
None
 1.06A 4wg0G-3fmpB:
undetectable
4wg0H-3fmpB:
undetectable
4wg0I-3fmpB:
undetectable		 4wg0G-3fmpB:
2.88
4wg0H-3fmpB:
2.88
4wg0I-3fmpB:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		5 / 11 ALA B 146
LEU B 150
LEU B 127
LEU B  97
LEU B  99
 ADP  B 480 (-3.4A)
None
None
None
None
 1.05A 4wg0K-3fmpB:
undetectable
4wg0L-3fmpB:
undetectable
4wg0M-3fmpB:
undetectable		 4wg0K-3fmpB:
2.88
4wg0L-3fmpB:
2.88
4wg0M-3fmpB:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		5 / 12 LEU B 168
PRO B 163
TYR B 196
ILE B 215
LEU B 192
 None
 1.41A 5ljbA-3fmpB:
undetectable		 5ljbA-3fmpB:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3fmp ATP-DEPENDENT RNA
HELICASE DDX19B
(Homo
sapiens) 		4 / 5 LEU B 103
GLN B 102
PHE B 188
PHE B  94
 None
 1.10A 6nmpP-3fmpB:
undetectable
6nmpW-3fmpB:
undetectable		 6nmpP-3fmpB:
20.04
6nmpW-3fmpB:
7.36