SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.79A 1c9sI-3fmqA:
undetectable
1c9sJ-3fmqA:
undetectable		 1c9sI-3fmqA:
13.14
1c9sJ-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.94A 1c9sN-3fmqA:
undetectable
1c9sO-3fmqA:
undetectable		 1c9sN-3fmqA:
13.14
1c9sO-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.93A 1c9sP-3fmqA:
undetectable
1c9sQ-3fmqA:
undetectable		 1c9sP-3fmqA:
13.14
1c9sQ-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 9 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.94A 1c9sQ-3fmqA:
undetectable
1c9sR-3fmqA:
undetectable		 1c9sQ-3fmqA:
13.14
1c9sR-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.80A 1c9sU-3fmqA:
undetectable
1c9sV-3fmqA:
undetectable		 1c9sU-3fmqA:
13.14
1c9sV-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.94A 1c9sL-3fmqA:
undetectable
1c9sV-3fmqA:
undetectable		 1c9sL-3fmqA:
13.14
1c9sV-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.96A 1gtfQ-3fmqA:
undetectable
1gtfR-3fmqA:
undetectable		 1gtfQ-3fmqA:
13.14
1gtfR-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 9 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.94A 1gtfR-3fmqA:
undetectable
1gtfS-3fmqA:
undetectable		 1gtfR-3fmqA:
13.14
1gtfS-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.95A 1gtfS-3fmqA:
undetectable
1gtfT-3fmqA:
undetectable		 1gtfS-3fmqA:
13.14
1gtfT-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 7 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.77A 1gtnA-3fmqA:
undetectable
1gtnK-3fmqA:
undetectable		 1gtnA-3fmqA:
13.14
1gtnK-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.76A 1gtnA-3fmqA:
undetectable
1gtnB-3fmqA:
undetectable		 1gtnA-3fmqA:
13.14
1gtnB-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.76A 1gtnE-3fmqA:
undetectable
1gtnF-3fmqA:
undetectable		 1gtnE-3fmqA:
13.14
1gtnF-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 ARG A  56
ALA A  51
ALA A  48
THR A 353
THR A 341
 None
 1.22A 1gtnH-3fmqA:
undetectable
1gtnI-3fmqA:
undetectable		 1gtnH-3fmqA:
13.14
1gtnI-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 ALA A  51
ALA A  48
THR A 353
THR A 341
 None
 0.74A 1gtnI-3fmqA:
undetectable
1gtnJ-3fmqA:
undetectable		 1gtnI-3fmqA:
13.14
1gtnJ-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.83A 1gtnP-3fmqA:
undetectable
1gtnQ-3fmqA:
undetectable		 1gtnP-3fmqA:
13.14
1gtnQ-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.90A 1gtnT-3fmqA:
undetectable
1gtnU-3fmqA:
undetectable		 1gtnT-3fmqA:
13.14
1gtnU-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 12 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.91A 1gtnL-3fmqA:
undetectable
1gtnV-3fmqA:
undetectable		 1gtnL-3fmqA:
13.14
1gtnV-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.79A 1utdB-3fmqA:
undetectable
1utdC-3fmqA:
undetectable		 1utdB-3fmqA:
13.14
1utdC-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.98A 1utdE-3fmqA:
undetectable
1utdF-3fmqA:
undetectable		 1utdE-3fmqA:
13.14
1utdF-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.78A 1utdF-3fmqA:
undetectable
1utdG-3fmqA:
undetectable		 1utdF-3fmqA:
13.14
1utdG-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.95A 1utdH-3fmqA:
undetectable
1utdI-3fmqA:
undetectable		 1utdH-3fmqA:
13.14
1utdI-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.76A 1utdI-3fmqA:
undetectable
1utdJ-3fmqA:
undetectable		 1utdI-3fmqA:
13.14
1utdJ-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.75A 1utdJ-3fmqA:
undetectable
1utdK-3fmqA:
undetectable		 1utdJ-3fmqA:
13.14
1utdK-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 12 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.96A 1utdL-3fmqA:
undetectable
1utdM-3fmqA:
undetectable		 1utdL-3fmqA:
13.14
1utdM-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 12 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.94A 1utdO-3fmqA:
undetectable
1utdP-3fmqA:
undetectable		 1utdO-3fmqA:
13.14
1utdP-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.95A 1utdP-3fmqA:
undetectable
1utdQ-3fmqA:
undetectable		 1utdP-3fmqA:
13.14
1utdQ-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.96A 1utdS-3fmqA:
undetectable
1utdT-3fmqA:
undetectable		 1utdS-3fmqA:
13.14
1utdT-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 251
ALA A 107
THR A 247
ILE A 204
GLY A 332
 None
 0.95A 1utdU-3fmqA:
undetectable
1utdV-3fmqA:
undetectable		 1utdU-3fmqA:
13.14
1utdV-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.93A 1utdL-3fmqA:
undetectable
1utdV-3fmqA:
undetectable		 1utdL-3fmqA:
13.14
1utdV-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 11 ILE A 212
GLU A 339
GLY A 132
THR A 133
HIS A  55
 None
FE  A 452 ( 2.4A)
None
None
None
 1.48A 2fn1B-3fmqA:
undetectable		 2fn1B-3fmqA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 TYR A 324
GLU A 243
HIS A 210
GLY A 209
 FUG  A 481 (-3.9A)
FE  A 451 ( 2.7A)
FE  A 451 (-3.4A)
None
 0.80A 2ha4A-3fmqA:
undetectable		 2ha4A-3fmqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 7 TYR A 324
GLU A 243
HIS A 210
GLY A 209
 FUG  A 481 (-3.9A)
FE  A 451 ( 2.7A)
FE  A 451 (-3.4A)
None
 0.78A 2ha4B-3fmqA:
undetectable		 2ha4B-3fmqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 7 SER A  42
LEU A 352
PHE A 239
GLY A  26
 None
 0.90A 2v0mC-3fmqA:
undetectable		 2v0mC-3fmqA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 SER A 238
TYR A 240
SER A 211
GLY A 219
GLY A 220
 None
 1.22A 3ixlA-3fmqA:
undetectable		 3ixlA-3fmqA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 5 PHE A 131
ILE A  79
GLY A  96
HIS A  55
 None
 1.28A 3r0lD-3fmqA:
undetectable		 3r0lD-3fmqA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 PHE A 148
VAL A 146
MET A 101
ILE A 129
 None
 1.07A 4a97C-3fmqA:
0.6		 4a97C-3fmqA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 PHE A 148
VAL A 146
MET A 101
ILE A 129
 None
 1.06A 4a97D-3fmqA:
undetectable		 4a97D-3fmqA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		3 / 3 ARG A  59
HIS A  55
TYR A 358
 None
 1.34A 4fu9A-3fmqA:
undetectable		 4fu9A-3fmqA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		3 / 3 TYR A 358
PHE A 131
ARG A  59
 None
 0.90A 4g19D-3fmqA:
undetectable		 4g19D-3fmqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 12 TYR A 358
ILE A  79
GLU A 339
GLY A 132
GLY A  96
 None
None
FE  A 452 ( 2.4A)
None
None
 1.25A 4hfpB-3fmqA:
undetectable		 4hfpB-3fmqA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 9 THR A 247
ALA A 107
ALA A 108
ILE A 330
GLY A 251
 None
None
FUG  A 481 ( 4.4A)
None
None
 1.01A 4qvqK-3fmqA:
undetectable
4qvqL-3fmqA:
undetectable		 4qvqK-3fmqA:
23.12
4qvqL-3fmqA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 9 THR A 247
ALA A 107
ALA A 108
ILE A 330
GLY A 251
 None
None
FUG  A 481 ( 4.4A)
None
None
 1.00A 4qvqY-3fmqA:
undetectable
4qvqZ-3fmqA:
undetectable		 4qvqY-3fmqA:
23.12
4qvqZ-3fmqA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 6 ALA A 225
ILE A 253
ILE A 187
VAL A 335
 None
 0.79A 4r21A-3fmqA:
undetectable		 4r21A-3fmqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		3 / 3 ARG A  49
GLN A  46
GLU A  41
 None
 0.84A 4tvtA-3fmqA:
undetectable		 4tvtA-3fmqA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 12 LEU A 327
PRO A  98
ASP A 141
ILE A 217
HIS A 210
 None
None
FE  A 452 ( 2.2A)
FUG  A 481 (-4.5A)
FE  A 451 (-3.4A)
 1.45A 5dv4A-3fmqA:
undetectable		 5dv4A-3fmqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.99A 5eevA-3fmqA:
undetectable
5eevB-3fmqA:
undetectable		 5eevA-3fmqA:
13.14
5eevB-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.99A 5eewA-3fmqA:
undetectable
5eewB-3fmqA:
undetectable		 5eewA-3fmqA:
13.14
5eewB-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.99A 5eexA-3fmqA:
undetectable
5eexB-3fmqA:
undetectable		 5eexA-3fmqA:
13.14
5eexB-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.99A 5eeyA-3fmqA:
undetectable
5eeyB-3fmqA:
undetectable		 5eeyA-3fmqA:
13.14
5eeyB-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.99A 5eezA-3fmqA:
undetectable
5eezB-3fmqA:
undetectable		 5eezA-3fmqA:
13.14
5eezB-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.99A 5ef0A-3fmqA:
undetectable
5ef0B-3fmqA:
undetectable		 5ef0A-3fmqA:
13.14
5ef0B-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.98A 5ef1A-3fmqA:
undetectable
5ef1B-3fmqA:
undetectable		 5ef1A-3fmqA:
13.14
5ef1B-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.99A 5ef2A-3fmqA:
undetectable
5ef2B-3fmqA:
undetectable		 5ef2A-3fmqA:
13.14
5ef2B-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 332
GLY A 251
ALA A 107
THR A 247
ILE A 204
 None
 0.98A 5ef3A-3fmqA:
undetectable
5ef3B-3fmqA:
undetectable		 5ef3A-3fmqA:
13.14
5ef3B-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		5 / 10 GLY A 251
ALA A 107
THR A 247
ILE A 204
SER A 105
 None
 1.20A 5ef3A-3fmqA:
undetectable
5ef3K-3fmqA:
undetectable		 5ef3A-3fmqA:
13.14
5ef3K-3fmqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 HIS A 261
SER A 308
HIS A 297
LEU A 298
 FUG  A 481 ( 4.9A)
None
None
None
 0.93A 5m8rB-3fmqA:
undetectable		 5m8rB-3fmqA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 8 HIS A 261
SER A 308
HIS A 297
LEU A 298
 FUG  A 481 ( 4.9A)
None
None
None
 0.95A 5m8rD-3fmqA:
undetectable		 5m8rD-3fmqA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 7 GLY A 209
HIS A 210
ASP A 141
HIS A 109
 None
FE  A 451 (-3.4A)
FE  A 452 ( 2.2A)
FUG  A 481 (-2.7A)
 0.74A 5nnwD-3fmqA:
undetectable		 5nnwD-3fmqA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 7 GLY A 209
HIS A 210
ASP A 141
HIS A 109
 None
FE  A 451 (-3.4A)
FE  A 452 ( 2.2A)
FUG  A 481 (-2.7A)
 0.76A 5no9D-3fmqA:
undetectable		 5no9D-3fmqA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 4 LYS A 149
LEU A 152
ALA A 147
LEU A 155
 None
 1.44A 6gnrA-3fmqA:
undetectable		 6gnrA-3fmqA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 3fmq METHIONINE
AMINOPEPTIDASE 2
(Encephalitozoon
cuniculi) 		4 / 4 LYS A 149
LEU A 152
ALA A 147
LEU A 155
 None
 1.44A 6gnrB-3fmqA:
undetectable		 6gnrB-3fmqA:
18.82