SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		5 / 12 PHE A  92
GLY A  94
ARG A 131
LEU A  83
GLU A  87
 None
 1.30A 1mj2A-3fmyA:
undetectable
1mj2B-3fmyA:
undetectable		 1mj2A-3fmyA:
26.37
1mj2B-3fmyA:
26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		4 / 7 ARG A 101
ALA A 107
ILE A  74
PRO A 109
 None
MEQ  A 108 ( 3.1A)
None
MEQ  A 108 ( 2.6A)
 0.93A 1oniA-3fmyA:
undetectable
1oniB-3fmyA:
undetectable		 1oniA-3fmyA:
20.14
1oniB-3fmyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		4 / 6 ARG A 101
ALA A 107
ILE A  74
PRO A 109
 None
MEQ  A 108 ( 3.1A)
None
MEQ  A 108 ( 2.6A)
 0.89A 1oniB-3fmyA:
undetectable
1oniC-3fmyA:
undetectable		 1oniB-3fmyA:
20.14
1oniC-3fmyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		4 / 7 ILE A  74
PRO A 109
ARG A 101
ALA A 107
 None
MEQ  A 108 ( 2.6A)
None
MEQ  A 108 ( 3.1A)
 0.91A 1oniD-3fmyA:
undetectable
1oniE-3fmyA:
undetectable		 1oniD-3fmyA:
20.14
1oniE-3fmyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		4 / 6 ARG A 101
ALA A 107
ILE A  74
PRO A 109
 None
MEQ  A 108 ( 3.1A)
None
MEQ  A 108 ( 2.6A)
 0.91A 1oniH-3fmyA:
undetectable
1oniI-3fmyA:
undetectable		 1oniH-3fmyA:
20.14
1oniI-3fmyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		4 / 7 ILE A  74
PRO A 109
ARG A 101
ALA A 107
 None
MEQ  A 108 ( 2.6A)
None
MEQ  A 108 ( 3.1A)
 0.87A 1oniG-3fmyA:
undetectable
1oniI-3fmyA:
undetectable		 1oniG-3fmyA:
20.14
1oniI-3fmyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		4 / 6 PHE A  99
ARG A 101
SER A  89
THR A 113
 None
 1.24A 2f7fA-3fmyA:
undetectable		 2f7fA-3fmyA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		5 / 10 ILE A  91
PHE A  99
LEU A 120
VAL A  77
LEU A 117
 None
 1.41A 2w98A-3fmyA:
undetectable		 2w98A-3fmyA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3fmy HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA
(YGIT/B3021)
(Escherichia
coli) 		4 / 8 LEU A 116
VAL A  77
LEU A  81
ALA A  88
 None
 0.75A 3uniB-3fmyA:
undetectable		 3uniB-3fmyA:
4.70