SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3fn1 NEDD8-CONJUGATING
ENZYME UBE2F
(Homo
sapiens) 		3 / 3 TRP B 130
VAL B  94
PRO B  95
 None
 0.73A 1rg1A-3fn1B:
undetectable		 1rg1A-3fn1B:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3fn1 NEDD8-CONJUGATING
ENZYME UBE2F
(Homo
sapiens) 		3 / 3 TRP B 130
VAL B  94
PRO B  95
 None
 0.71A 1rh0A-3fn1B:
undetectable		 1rh0A-3fn1B:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 3fn1 NEDD8-CONJUGATING
ENZYME UBE2F
(Homo
sapiens) 		4 / 5 CYH B 100
TYR B 179
THR B  68
THR B 110
 None
 1.47A 3q07B-3fn1B:
undetectable		 3q07B-3fn1B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3fn1 NEDD8-CONJUGATING
ENZYME UBE2F
(Homo
sapiens) 		4 / 5 TYR B  75
HIS B 164
LEU B 166
PRO B 107
 None
 1.30A 5csyB-3fn1B:
undetectable		 5csyB-3fn1B:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3fn1 NEDD8-CONJUGATING
ENZYME UBE2F
(Homo
sapiens) 		5 / 12 PHE B 147
THR B 102
ILE B 104
PRO B 107
THR B  51
 None
 1.05A 5eajB-3fn1B:
undetectable		 5eajB-3fn1B:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3fn1 NEDD8-CONJUGATING
ENZYME UBE2F
(Homo
sapiens) 		5 / 12 ILE B 104
PHE B 172
PHE B 153
ILE B 115
LEU B 146
 None
 1.13A 6dwnC-3fn1B:
undetectable		 6dwnC-3fn1B:
18.18