SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_B_ROFB102_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 TYR A 316
MET A 347
LEU A 374
TYR A 412
SER A 553
 None
 1.35A 1xmuB-3fn9A:
undetectable		 1xmuB-3fn9A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 TYR A 316
MET A 347
LEU A 374
TYR A 412
SER A 553
 None
 1.28A 1xoqA-3fn9A:
undetectable		 1xoqA-3fn9A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 SER A 590
TYR A 594
TYR A 504
HIS A 537
 None
 1.14A 2bteD-3fn9A:
undetectable		 2bteD-3fn9A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 6 LEU A 521
ASN A 689
LYS A 535
PHE A 532
 None
 1.23A 2jn3A-3fn9A:
undetectable		 2jn3A-3fn9A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 SER A 590
TYR A 594
TYR A 504
HIS A 537
 None
 1.38A 2v0gA-3fn9A:
undetectable		 2v0gA-3fn9A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 ALA A 118
VAL A 113
GLY A 133
THR A 134
 None
 0.65A 2xrzB-3fn9A:
undetectable		 2xrzB-3fn9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 TYR A 472
ASN A 451
VAL A 420
VAL A 383
LEU A 163
 None
 1.28A 3casA-3fn9A:
9.0		 3casA-3fn9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 MET A  69
MET A 576
PHE A 164
 None
 1.32A 3gn8A-3fn9A:
undetectable		 3gn8A-3fn9A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ASN A 451
ASN A 418
GLU A 503
 None
 0.91A 3kpdC-3fn9A:
undetectable		 3kpdC-3fn9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ASN A 451
ASN A 418
GLU A 503
 None
 0.90A 3kpdB-3fn9A:
undetectable		 3kpdB-3fn9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 HIS A 324
GLU A 503
ASN A 418
 None
 0.99A 4bupB-3fn9A:
undetectable		 4bupB-3fn9A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 HIS A 455
GLU A 477
HIS A 417
THR A 502
SER A 449
 None
 1.34A 4hvcA-3fn9A:
undetectable		 4hvcA-3fn9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 VAL A 156
PRO A 154
GLU A 392
TYR A 426
 None
 1.03A 4lb2A-3fn9A:
undetectable		 4lb2A-3fn9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 TYR A 366
ARG A 172
SER A 362
 None
 1.21A 4lf7I-3fn9A:
undetectable
4lf7J-3fn9A:
undetectable		 4lf7I-3fn9A:
13.04
4lf7J-3fn9A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 TYR A 366
ARG A 172
SER A 362
 None
 1.21A 4lf8I-3fn9A:
undetectable
4lf8J-3fn9A:
undetectable		 4lf8I-3fn9A:
13.04
4lf8J-3fn9A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 6 ASN A 689
GLU A 687
GLU A 615
GLU A 515
 None
 1.38A 4mi4A-3fn9A:
undetectable		 4mi4A-3fn9A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 6 PHE A  35
GLY A  81
TYR A  83
ALA A 148
 None
 1.18A 4yshB-3fn9A:
undetectable		 4yshB-3fn9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 SER A 126
TYR A 125
PRO A 381
PHE A 128
 None
 1.10A 5aclA-3fn9A:
5.8		 5aclA-3fn9A:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ILE A 346
ILE A 376
MET A 558
 None
 0.69A 5i9yA-3fn9A:
undetectable		 5i9yA-3fn9A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 9 ILE A 230
PHE A 259
ASN A 407
ILE A 196
 None
 1.02A 5lg3I-3fn9A:
undetectable		 5lg3I-3fn9A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 HIS A 324
GLU A 503
ASN A 418
 None
 0.94A 5wbvA-3fn9A:
undetectable		 5wbvA-3fn9A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 HIS A 324
GLU A 503
ASN A 418
 None
 0.95A 5wbvB-3fn9A:
undetectable		 5wbvB-3fn9A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 6 PHE A 164
GLY A 165
GLN A 325
TYR A 171
 None
 1.08A 6ag0A-3fn9A:
10.9		 6ag0A-3fn9A:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 6 PHE A 164
GLY A 165
GLN A 325
TYR A 171
 None
 1.12A 6ag0C-3fn9A:
10.7		 6ag0C-3fn9A:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 186
GLY A 104
VAL A 105
THR A 120
GLY A 119
 None
 1.03A 6brdC-3fn9A:
undetectable		 6brdC-3fn9A:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 5 GLN A 253
THR A 254
THR A 187
GLY A 251
 None
 1.15A 6gbnC-3fn9A:
undetectable		 6gbnC-3fn9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 3fn9 PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 LEU A 100
TRP A 175
GLY A 104
PHE A 102
ILE A  60
 None
 1.43A 6qyaB-3fn9A:
undetectable		 6qyaB-3fn9A:
18.21