SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		3 / 3 GLY A 245
ASP A 262
ASN A 243
 None
 0.67A 1vq1A-3fnaA:
undetectable		 1vq1A-3fnaA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 5 LEU A 329
ASP A 328
GLY A 322
ALA A 297
ILE A 216
 None
 1.40A 2aohB-3fnaA:
undetectable		 2aohB-3fnaA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 289
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
 0.94A 3kpbA-3fnaA:
15.6		 3kpbA-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		7 / 12 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 289
ILE A 309
SER A 311
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
AMP  A 401 (-4.4A)
None
 1.36A 3kpbA-3fnaA:
15.6		 3kpbA-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 289
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
 0.95A 3kpbC-3fnaA:
15.6		 3kpbC-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		7 / 12 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 289
ILE A 309
SER A 311
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
AMP  A 401 (-4.4A)
None
 1.36A 3kpbC-3fnaA:
15.6		 3kpbC-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 10 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 289
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
 0.95A 3kpbD-3fnaA:
15.2		 3kpbD-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		7 / 10 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 289
ILE A 309
SER A 311
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
AMP  A 401 (-4.4A)
None
 1.35A 3kpbD-3fnaA:
15.2		 3kpbD-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 289
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
 0.93A 3kpdB-3fnaA:
15.1		 3kpdB-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
ASP A 264
THR A 285
ILE A 309
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
AMP  A 401 (-4.4A)
 1.07A 3kpdB-3fnaA:
15.1		 3kpdB-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
ASP A 264
ILE A 309
VAL A 312
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-4.4A)
None
 0.82A 3kpdC-3fnaA:
16.3		 3kpdC-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
ASP A 264
THR A 285
VAL A 312
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-2.7A)
AMP  A 401 (-3.1A)
None
 0.83A 3kpdC-3fnaA:
16.3		 3kpdC-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
ILE A 289
ILE A 309
VAL A 312
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
None
AMP  A 401 (-4.4A)
None
 1.02A 3kpdC-3fnaA:
16.3		 3kpdC-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 259
THR A 261
THR A 285
ILE A 289
VAL A 312
 AMP  A 401 (-4.8A)
AMP  A 401 (-3.1A)
AMP  A 401 (-3.1A)
None
None
 0.96A 3kpdC-3fnaA:
16.3		 3kpdC-3fnaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		3 / 3 LEU A 320
HIS A 319
MET A 254
 None
 0.95A 3thrD-3fnaA:
undetectable		 3thrD-3fnaA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		4 / 8 GLY A 322
VAL A 323
HIS A 218
ILE A 216
 None
 0.87A 4fglD-3fnaA:
undetectable		 4fglD-3fnaA:
18.80