SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 9 TYR A  52
PHE A  79
ASP A 155
MET A 211
ASP A 214
TRP A 322
 None
 1.02A 1e9lA-3fndA:
31.5		 1e9lA-3fndA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 9 TYR A  52
PHE A  79
ASP A 155
MET A 211
TYR A 213
ASP A 214
 None
 0.88A 1e9lA-3fndA:
31.5		 1e9lA-3fndA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		7 / 11 TYR A  52
PHE A  79
ASP A 155
MET A 211
TYR A 213
TYR A 256
TRP A 322
 None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.91A 2a3aA-3fndA:
31.5		 2a3aA-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		8 / 11 TYR A  52
PHE A  79
GLU A 157
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.49A 2a3aA-3fndA:
31.5		 2a3aA-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		7 / 9 PHE A  79
GLU A 157
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.56A 2a3aB-3fndA:
31.6		 2a3aB-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1433_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 159
MET A 211
ASP A 214
PHE A 218
 None
 1.19A 2a3bA-3fndA:
31.5		 2a3bA-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		7 / 11 TYR A  52
PHE A  79
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.44A 2a3bA-3fndA:
31.4		 2a3bA-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 10 PHE A  79
ASP A 155
GLU A 157
MET A 211
TYR A 213
TRP A 322
 None
 1.16A 2a3bB-3fndA:
31.5		 2a3bB-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 10 PHE A  79
ASP A 155
MET A 211
TYR A 213
TYR A 256
TRP A 322
 None
None
None
None
GOL  A 356 (-4.3A)
None
 1.01A 2a3bB-3fndA:
31.5		 2a3bB-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 10 PHE A  79
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
GOL  A 356 (-4.3A)
None
 0.43A 2a3bB-3fndA:
31.5		 2a3bB-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		7 / 12 TYR A  52
PHE A  79
ASP A 155
GLU A 157
MET A 211
TYR A 213
TRP A 322
 None
 1.12A 2a3cA-3fndA:
31.4		 2a3cA-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		7 / 12 TYR A  52
PHE A  79
ASP A 155
MET A 211
TYR A 213
TYR A 256
TRP A 322
 None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.97A 2a3cA-3fndA:
31.4		 2a3cA-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		7 / 12 TYR A  52
PHE A  79
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.44A 2a3cA-3fndA:
31.4		 2a3cA-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 12 PHE A  79
ASP A 155
GLU A 157
MET A 211
TYR A 213
TRP A 322
 None
 1.15A 2a3cB-3fndA:
31.6		 2a3cB-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 12 PHE A  79
ASP A 155
MET A 211
TYR A 213
TYR A 256
TRP A 322
 None
None
None
None
GOL  A 356 (-4.3A)
None
 0.99A 2a3cB-3fndA:
31.6		 2a3cB-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 12 PHE A  79
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
GOL  A 356 (-4.3A)
None
 0.38A 2a3cB-3fndA:
31.6		 2a3cB-3fndA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 9 TYR A  52
PHE A  79
ASP A 155
GLU A 157
TYR A 213
TRP A 322
 None
 0.53A 2uy4A-3fndA:
18.1		 2uy4A-3fndA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 337
SER A 212
PHE A 231
ASP A 234
 None
 1.14A 2vn1B-3fndA:
undetectable		 2vn1B-3fndA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A  53
PHE A 325
LEU A  55
PRO A  65
 None
 0.93A 2vq5B-3fndA:
undetectable		 2vq5B-3fndA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 11 TYR A  52
PHE A  79
ASP A 155
GLU A 157
TYR A 213
TRP A 322
 None
 0.79A 2xtkA-3fndA:
19.5		 2xtkA-3fndA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 10 TYR A  52
PHE A  79
ASP A 155
GLU A 157
TYR A 213
TRP A 322
 None
 0.62A 2xtkB-3fndA:
19.5		 2xtkB-3fndA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		6 / 11 TYR A  52
PHE A  79
ASP A 155
TYR A 213
TYR A 256
TRP A 322
 None
None
None
None
GOL  A 356 (-4.3A)
None
 1.01A 3g6mA-3fndA:
31.6		 3g6mA-3fndA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		8 / 11 TYR A  52
PHE A  79
GLU A 157
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.51A 3g6mA-3fndA:
31.6		 3g6mA-3fndA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 159
LEU A 169
TYR A 156
TYR A 197
 None
 1.25A 3po7A-3fndA:
undetectable		 3po7A-3fndA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		8 / 11 PHE A  79
ASP A 155
GLU A 157
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.47A 3wqvA-3fndA:
33.5		 3wqvA-3fndA:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		8 / 11 PHE A  79
ASP A 155
GLU A 157
MET A 211
TYR A 213
ASP A 214
TYR A 256
TRP A 322
 None
None
None
None
None
None
GOL  A 356 (-4.3A)
None
 0.48A 3wqwA-3fndA:
33.5		 3wqwA-3fndA:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASN A 165
LEU A 169
ARG A 133
GLY A 121
 None
 0.93A 4cp3A-3fndA:
undetectable
4cp3B-3fndA:
undetectable		 4cp3A-3fndA:
18.93
4cp3B-3fndA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		5 / 8 PHE A  79
GLU A 157
TYR A 213
ASP A 214
TRP A 322
 None
 0.46A 5gqbA-3fndA:
29.7		 5gqbA-3fndA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A  67
ILE A 111
HIS A  74
VAL A 109
 None
 0.91A 5jmnA-3fndA:
undetectable		 5jmnA-3fndA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 111
PHE A  64
SER A  99
ALA A 104
 None
 1.15A 5msdA-3fndA:
undetectable		 5msdA-3fndA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 154
ALA A 173
LEU A 176
ILE A 137
 None
 0.85A 5mvmB-3fndA:
undetectable
5mvmC-3fndA:
undetectable		 5mvmB-3fndA:
14.72
5mvmC-3fndA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 114
LEU A 324
LEU A  55
ASP A  56
ILE A 321
 None
 1.10A 6dm0B-3fndA:
2.8
6dm0C-3fndA:
3.0		 6dm0B-3fndA:
14.34
6dm0C-3fndA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3fnd CHITINASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A  72
ASN A 209
LEU A 112
 None
 0.72A 6exiD-3fndA:
undetectable		 6exiD-3fndA:
15.38