SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fnr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 8 LEU A 192
PHE A 200
GLY A 201
TRP A 216
 None
 0.63A 1fapB-3fnrA:
undetectable		 1fapB-3fnrA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 LEU A 477
LEU A 480
ALA A 481
MET A 520
ILE A 522
 None
 1.11A 1g50A-3fnrA:
undetectable		 1g50A-3fnrA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 10 LEU A  82
LEU A  85
ALA A  86
LEU A 508
LEU A 443
 None
 1.33A 1gwrA-3fnrA:
undetectable		 1gwrA-3fnrA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 LEU A 477
LEU A 461
ASN A 415
VAL A 411
TYR A 384
 None
 1.44A 1mrlA-3fnrA:
undetectable
1mrlB-3fnrA:
undetectable		 1mrlA-3fnrA:
18.98
1mrlB-3fnrA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 8 PHE A 333
LEU A 271
GLY A 277
ASP A 278
 None
 1.01A 1rmtC-3fnrA:
undetectable		 1rmtC-3fnrA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 8 TYR A 149
ARG A 307
GLU A 109
ASP A 297
 None
None
None
GOL  A 539 (-3.4A)
 1.18A 1s3zA-3fnrA:
undetectable
1s3zB-3fnrA:
undetectable		 1s3zA-3fnrA:
14.81
1s3zB-3fnrA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 ILE A 421
ALA A 417
PHE A 487
PHE A 506
VAL A 424
 None
 1.22A 2w3aA-3fnrA:
undetectable		 2w3aA-3fnrA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 7 LEU A 108
PHE A 144
LEU A 133
PHE A 129
 None
 1.07A 3asoP-3fnrA:
3.2
3asoW-3fnrA:
undetectable		 3asoP-3fnrA:
20.22
3asoW-3fnrA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 7 LEU A 351
SER A 350
ARG A 125
ILE A 121
 None
 0.91A 3ln1B-3fnrA:
undetectable		 3ln1B-3fnrA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 VAL A 349
LEU A 351
VAL A 128
GLY A 126
ALA A 124
 None
 1.22A 3pghB-3fnrA:
undetectable		 3pghB-3fnrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		6 / 12 VAL A 373
VAL A 349
LEU A 351
VAL A 128
GLY A 126
ALA A 124
 None
 1.32A 3pghC-3fnrA:
undetectable		 3pghC-3fnrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 VAL A 373
VAL A 349
LEU A 351
VAL A 128
ALA A 124
 None
 1.04A 3rr3A-3fnrA:
undetectable		 3rr3A-3fnrA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 VAL A 373
VAL A 349
LEU A 351
VAL A 128
ALA A 124
 None
 1.03A 3rr3B-3fnrA:
undetectable		 3rr3B-3fnrA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 VAL A 373
VAL A 349
LEU A 351
VAL A 128
ALA A 124
 None
 1.05A 3rr3C-3fnrA:
undetectable		 3rr3C-3fnrA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 VAL A 373
VAL A 349
LEU A 351
VAL A 128
ALA A 124
 None
 1.04A 3rr3D-3fnrA:
undetectable		 3rr3D-3fnrA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 5 GLN A 403
TYR A 412
LEU A 352
LYS A 353
 None
 1.32A 3sugA-3fnrA:
undetectable		 3sugA-3fnrA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 6 LEU A 108
PHE A 144
LEU A 133
PHE A 129
 None
 1.07A 3wg7C-3fnrA:
undetectable
3wg7J-3fnrA:
undetectable		 3wg7C-3fnrA:
20.22
3wg7J-3fnrA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 LEU A 341
LEU A 107
GLU A 147
ARG A 307
ASP A 303
 None
 1.32A 4b9zA-3fnrA:
undetectable		 4b9zA-3fnrA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 8 LEU A 192
PHE A 200
TRP A 216
ASP A 215
 None
 0.77A 4drjB-3fnrA:
3.2		 4drjB-3fnrA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 LEU A 470
LEU A 477
LEU A 136
LEU A 461
ALA A 464
 None
 1.16A 4p65B-3fnrA:
undetectable
4p65D-3fnrA:
undetectable
4p65G-3fnrA:
undetectable
4p65H-3fnrA:
undetectable		 4p65B-3fnrA:
4.83
4p65D-3fnrA:
4.83
4p65G-3fnrA:
5.64
4p65H-3fnrA:
4.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 LEU A 395
VAL A 373
ILE A 399
ILE A 121
GLY A 122
 None
 1.00A 4y8wC-3fnrA:
2.2		 4y8wC-3fnrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 7 LEU A 108
PHE A 106
PHE A 144
PHE A 129
 None
 0.90A 5b1bP-3fnrA:
2.8
5b1bW-3fnrA:
undetectable		 5b1bP-3fnrA:
20.22
5b1bW-3fnrA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 6 LEU A 351
SER A 350
ARG A 125
ILE A 121
 None
 0.91A 5jw1A-3fnrA:
undetectable		 5jw1A-3fnrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 5 ILE A 164
PHE A 204
SER A 212
ALA A 196
 None
 1.09A 5msdA-3fnrA:
2.3		 5msdA-3fnrA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		4 / 7 LEU A 108
PHE A 106
PHE A 144
PHE A 129
 None
 0.95A 5z84C-3fnrA:
3.3
5z84J-3fnrA:
undetectable		 5z84C-3fnrA:
20.22
5z84J-3fnrA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3fnr ARGINYL-TRNA
SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 ASP A 278
ASP A 297
ASN A 114
 None
GOL  A 539 (-3.4A)
None
 0.75A 6gngB-3fnrA:
3.0		 6gngB-3fnrA:
21.60