SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fo8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 4 ILE D 311
LEU D 195
VAL D 223
ILE D 323
 None
 0.87A 1fm6D-3fo8D:
undetectable		 1fm6D-3fo8D:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 ILE D 150
ILE D 151
GLU D 100
TYR D 101
ASN D 213
 None
 1.26A 1jtxA-3fo8D:
undetectable		 1jtxA-3fo8D:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 GLU D 202
ASP D 312
MET D 205
ILE D 193
THR D 326
 None
 1.38A 1s14A-3fo8D:
undetectable		 1s14A-3fo8D:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 GLY D 258
ILE D 150
ILE D  99
GLY D  97
ALA D 152
 None
 1.04A 1sh9B-3fo8D:
undetectable		 1sh9B-3fo8D:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 7 ILE D 236
ILE D  95
LEU D 214
ILE D 219
 None
 0.87A 2q83A-3fo8D:
undetectable		 2q83A-3fo8D:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 7 VAL D 268
ILE D 282
ALA D 280
THR D 264
 None
None
None
ACT  D 601 (-4.1A)
 0.80A 2xrzB-3fo8D:
undetectable		 2xrzB-3fo8D:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 7 SER D  93
PHE D 210
ILE D 193
PRO D 220
GLY D 221
 None
 1.14A 2y7kA-3fo8D:
undetectable		 2y7kA-3fo8D:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 PRO D 331
PHE D 210
LYS D 215
 None
 1.14A 3bjwG-3fo8D:
undetectable		 3bjwG-3fo8D:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 GLY D 221
ILE D 193
SER D  93
ASN D 329
LEU D 214
 None
 1.38A 3cjtK-3fo8D:
undetectable		 3cjtK-3fo8D:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 11 ASP D 114
ILE D 182
LEU D 178
VAL D 134
ILE D 131
 None
 0.76A 3em4U-3fo8D:
undetectable		 3em4U-3fo8D:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 ASP D 114
ILE D 182
LEU D 178
VAL D 134
ILE D 131
 None
 0.93A 3em4V-3fo8D:
undetectable		 3em4V-3fo8D:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 GLU D 202
ASP D 312
MET D 205
ILE D 193
THR D 326
 None
 1.48A 3lpsA-3fo8D:
undetectable		 3lpsA-3fo8D:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 8 PRO D 256
SER D  93
LEU D 340
LYS D 233
 None
 1.03A 3lsfH-3fo8D:
undetectable		 3lsfH-3fo8D:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 PHE D 334
GLY D 336
ILE D 238
ILE D 254
LEU D 340
 None
 1.09A 4pd4C-3fo8D:
undetectable		 4pd4C-3fo8D:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 SER D 320
GLU D 357
GLU D 229
 None
 0.86A 4ymgB-3fo8D:
undetectable		 4ymgB-3fo8D:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 8 SER D 191
GLY D 342
ILE D 236
GLY D 231
 None
 0.81A 5alcL-3fo8D:
undetectable		 5alcL-3fo8D:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 PRO D 253
ILE D 171
SER D 335
 None
 0.78A 5fsaA-3fo8D:
undetectable		 5fsaA-3fo8D:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR D 297
SER D 277
TYR D 279
 None
 0.87A 5jsdA-3fo8D:
undetectable		 5jsdA-3fo8D:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR D 297
SER D 277
TYR D 279
 None
 0.88A 5jsdB-3fo8D:
undetectable		 5jsdB-3fo8D:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR D 297
SER D 277
TYR D 279
 None
 0.87A 5jsdC-3fo8D:
undetectable		 5jsdC-3fo8D:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR D 297
SER D 277
TYR D 279
 None
 0.88A 5jseA-3fo8D:
undetectable		 5jseA-3fo8D:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR D 297
SER D 277
TYR D 279
 None
 0.88A 5jseB-3fo8D:
undetectable		 5jseB-3fo8D:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR D 297
SER D 277
TYR D 279
 None
 0.88A 5jseC-3fo8D:
undetectable		 5jseC-3fo8D:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 3fo8 TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 ARG D 284
VAL D 283
ILE D 281
VAL D 239
ILE D 238
 ACT  D 601 (-3.8A)
None
None
None
None
 1.48A 6gsdA-3fo8D:
undetectable		 6gsdA-3fo8D:
16.46