SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		6 / 10 GLY A  32
SER A  99
MET A 100
PHE A 164
THR A 231
HIS A 258
 CL  A 401 ( 4.1A)
CL  A 401 (-2.9A)
CL  A 401 (-4.5A)
None
None
None
 0.54A 1a8uA-3fobA:
45.3		 1a8uA-3fobA:
48.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		6 / 10 GLY A  32
SER A  99
PHE A 164
TRP A  33
THR A 231
HIS A 258
 CL  A 401 ( 4.1A)
CL  A 401 (-2.9A)
None
None
None
None
 1.31A 1a8uA-3fobA:
45.3		 1a8uA-3fobA:
48.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		6 / 10 GLY A  32
SER A  99
MET A 100
PHE A 164
THR A 231
HIS A 258
 CL  A 401 ( 4.1A)
CL  A 401 (-2.9A)
CL  A 401 (-4.5A)
None
None
None
 0.52A 1a8uB-3fobA:
45.2		 1a8uB-3fobA:
48.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		6 / 10 GLY A  32
SER A  99
PHE A 164
TRP A  33
THR A 231
HIS A 258
 CL  A 401 ( 4.1A)
CL  A 401 (-2.9A)
None
None
None
None
 1.37A 1a8uB-3fobA:
45.2		 1a8uB-3fobA:
48.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 6 THR A 231
PHE A 168
PHE A  98
GLY A  32
 None
None
None
CL  A 401 ( 4.1A)
 1.15A 1icuC-3fobA:
undetectable
1icuD-3fobA:
undetectable		 1icuC-3fobA:
22.81
1icuD-3fobA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		5 / 10 GLY A  32
HIS A  31
ALA A 125
ASN A 261
ALA A 123
 CL  A 401 ( 4.1A)
None
None
None
None
 0.95A 1likA-3fobA:
undetectable		 1likA-3fobA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		5 / 12 PHE A  98
SER A 228
VAL A 178
ALA A 262
HIS A 264
 None
 1.30A 1q23A-3fobA:
undetectable
1q23B-3fobA:
undetectable		 1q23A-3fobA:
19.86
1q23B-3fobA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 7 PHE A 217
ILE A 219
THR A 241
GLY A  97
 None
 0.86A 2v0mB-3fobA:
undetectable		 2v0mB-3fobA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 5 PHE A 168
SER A  65
PHE A  98
ILE A  16
 None
 1.28A 2v0mD-3fobA:
undetectable		 2v0mD-3fobA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 7 TYR A  72
GLU A  70
GLU A   9
ARG A  60
 None
 1.13A 4mi4B-3fobA:
undetectable
4mi4C-3fobA:
undetectable		 4mi4B-3fobA:
18.41
4mi4C-3fobA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 8 TYR A  72
GLU A  70
GLU A   9
ARG A  60
 None
 1.12A 4mj8B-3fobA:
undetectable
4mj8C-3fobA:
undetectable		 4mj8B-3fobA:
18.91
4mj8C-3fobA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 7 PHE A  62
ASP A  58
PRO A  68
ILE A  30
 None
 1.00A 4pcuA-3fobA:
undetectable		 4pcuA-3fobA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 7 TYR A  72
GLU A  70
GLU A   9
ARG A  60
 None
 1.19A 4r87J-3fobA:
1.3
4r87L-3fobA:
undetectable		 4r87J-3fobA:
18.91
4r87L-3fobA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 4 ALA A 106
VAL A 126
GLY A 238
THR A 241
 None
 1.14A 4ubeA-3fobA:
4.7		 4ubeA-3fobA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 5 PHE A 217
PRO A 220
VAL A 120
PHE A 275
 None
 1.27A 4w5oA-3fobA:
3.2		 4w5oA-3fobA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 5 PHE A 217
PRO A 220
VAL A 120
PHE A 275
 None
 1.27A 4z4dA-3fobA:
3.8		 4z4dA-3fobA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		4 / 5 PHE A 217
PRO A 220
VAL A 120
PHE A 275
 None
 1.26A 4z4eA-3fobA:
3.2		 4z4eA-3fobA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		5 / 12 ALA A 262
PHE A 182
THR A 165
GLY A  32
LEU A  35
 None
None
None
CL  A 401 ( 4.1A)
None
 1.16A 5m54E-3fobA:
4.5		 5m54E-3fobA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3fob BROMOPEROXIDASE
(Bacillus
anthracis) 		5 / 12 GLY A  32
SER A  99
PHE A 169
PHE A 168
ASN A 186
 CL  A 401 ( 4.1A)
CL  A 401 (-2.9A)
None
None
None
 1.44A 6a94A-3fobA:
undetectable		 6a94A-3fobA:
21.77