SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fot'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 11 PRO A 231
SER A 236
GLY A 193
ASP A 190
LEU A  53
 None
 1.24A 1jzsA-3fotA:
undetectable		 1jzsA-3fotA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 12 LEU A 322
LEU A 316
VAL A 315
ILE A 365
SER A 388
 None
 1.10A 1s19A-3fotA:
undetectable		 1s19A-3fotA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 12 HIS A 282
ILE A 281
LEU A 476
ILE A 314
SER A 289
 None
 1.21A 1zq9A-3fotA:
undetectable		 1zq9A-3fotA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 7 PHE A 428
GLN A 471
TYR A  51
GLU A 417
 None
 1.27A 2aowA-3fotA:
undetectable		 2aowA-3fotA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  51
ASN A  46
GLU A  44
VAL A  96
 None
 0.86A 2fl5E-3fotA:
undetectable
2fl5F-3fotA:
undetectable		 2fl5E-3fotA:
18.18
2fl5F-3fotA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 7 ALA A 408
GLY A 410
VAL A 413
ASP A 249
LEU A 244
 None
 1.46A 2uyqA-3fotA:
undetectable		 2uyqA-3fotA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 11 LEU A 386
ILE A 292
PHE A 517
ALA A 295
THR A 298
 None
 1.15A 2v0mD-3fotA:
undetectable		 2v0mD-3fotA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 7 VAL A 462
ARG A 484
ASN A 442
VAL A 198
 None
 0.92A 2y05A-3fotA:
undetectable
2y05B-3fotA:
undetectable		 2y05A-3fotA:
20.97
2y05B-3fotA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 8 VAL A  40
VAL A  96
PHE A 188
HIS A 186
 None
None
None
GOL  A 524 (-3.5A)
 1.06A 3fhxB-3fotA:
undetectable		 3fhxB-3fotA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		3 / 3 GLU A 179
ASP A 136
ASP A 466
 None
 0.61A 3jb2A-3fotA:
undetectable		 3jb2A-3fotA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 5 VAL A 468
ILE A 437
MET A 514
ARG A 278
 None
GOL  A 524 ( 4.2A)
None
None
 1.48A 3oezA-3fotA:
undetectable		 3oezA-3fotA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		3 / 3 TYR A  54
LEU A  74
LYS A  75
 None
None
SO4  A 528 ( 3.8A)
 0.79A 3sueD-3fotA:
undetectable		 3sueD-3fotA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 7 GLU A 417
GLN A 358
PRO A 427
TYR A 263
 None
GOL  A 524 ( 4.3A)
None
None
 1.08A 3ugrA-3fotA:
undetectable		 3ugrA-3fotA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		3 / 3 PRO A 277
ASP A 495
GLU A 143
 None
 0.87A 3v4tC-3fotA:
undetectable		 3v4tC-3fotA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		3 / 3 ASN A  46
TRP A  98
ASP A  52
 None
 1.32A 4a7tA-3fotA:
undetectable
4a7tF-3fotA:
undetectable		 4a7tA-3fotA:
16.63
4a7tF-3fotA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		3 / 3 PHE A 197
VAL A 462
ILE A 465
 None
 0.65A 4emaA-3fotA:
undetectable		 4emaA-3fotA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JXC_A_SAMA402_0
(FEFE-HYDROGENASE
MATURASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 12 TYR A  54
GLY A 144
ARG A 145
ILE A 180
LEU A 137
 None
 1.36A 4jxcA-3fotA:
undetectable		 4jxcA-3fotA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 12 ALA A 389
LEU A 309
SER A 307
SER A 509
ILE A 510
 None
 1.05A 4ky8C-3fotA:
undetectable		 4ky8C-3fotA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		3 / 3 ARG A  31
TRP A  19
ILE A 106
 None
 0.76A 4mwxA-3fotA:
undetectable		 4mwxA-3fotA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 12 ILE A 478
ILE A  39
LEU A 421
SER A 335
ASN A 262
 None
 0.96A 4o1eB-3fotA:
undetectable		 4o1eB-3fotA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 11 ILE A 314
CYH A 390
HIS A 308
LEU A 309
LEU A 480
 None
 1.06A 4p65E-3fotA:
undetectable
4p65F-3fotA:
undetectable
4p65J-3fotA:
undetectable
4p65L-3fotA:
undetectable		 4p65E-3fotA:
4.38
4p65F-3fotA:
6.54
4p65J-3fotA:
6.54
4p65L-3fotA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 5 GLU A  37
ARG A  31
PHE A 353
ARG A 342
 None
 1.30A 5jcnA-3fotA:
0.0		 5jcnA-3fotA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		4 / 6 GLU A  37
ARG A  31
PHE A 353
ARG A 342
 None
 1.31A 5jcnB-3fotA:
undetectable		 5jcnB-3fotA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 10 ILE A 437
ALA A 477
LEU A 435
ILE A  39
TYR A  51
 GOL  A 524 ( 4.2A)
None
None
None
None
 1.01A 5mvmD-3fotA:
undetectable
5mvmE-3fotA:
undetectable		 5mvmD-3fotA:
11.06
5mvmE-3fotA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3fot 15-O-ACETYLTRANSFERA
SE
(Fusarium
sporotrichioides) 		5 / 12 ILE A 450
LEU A  82
LEU A 181
THR A  57
LEU A  59
 None
 1.25A 5xxiA-3fotA:
undetectable		 5xxiA-3fotA:
22.70