SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZU_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3fov	UPF0102 PROTEIN RPA0323 (Rhodopseudomonas palustris)	5 / 12	ALA A 128 GLN A 84 ILE A 51 HIS A 101 LEU A 95	None	1.13A	3dzuA-3fovA: undetectable	3dzuA-3fovA: 14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM6_A_017A200_2 (PROTEASE)	3fov	UPF0102 PROTEIN RPA0323 (Rhodopseudomonas palustris)	6 / 12	ARG A 120 LEU A 112 ALA A 28 VAL A 64 PRO A 123 ILE A 111	None	1.46A	3em6B-3fovA: undetectable	3em6B-3fovA: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UUD_A_ESTA600_1 (ESTROGEN RECEPTOR)	3fov	UPF0102 PROTEIN RPA0323 (Rhodopseudomonas palustris)	5 / 11	LEU A 40 ALA A 62 LEU A 60 GLY A 36 LEU A 32	None	1.10A	3uudA-3fovA: undetectable	3uudA-3fovA: 17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DQF_B_017B101_1 (ASPARTYL PROTEASE)	3fov	UPF0102 PROTEIN RPA0323 (Rhodopseudomonas palustris)	6 / 12	ARG A 120 LEU A 112 ALA A 28 VAL A 64 PRO A 123 ILE A 111	None	1.49A	4dqfA-3fovA: undetectable	4dqfA-3fovA: 22.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3DZU_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3fov","UPF0102 PROTEIN RPA0323","Rhodopseudomonas palustris",5,"ALA A 128;GLN A  84;ILE A  51;HIS A 101;LEU A  95","None","1.13A","3dzuA-3fovA:undetectable","3dzuA-3fovA:14.58"],["3EM6_A_017A200_2","PROTEASE;PROTEASE","3fov","UPF0102 PROTEIN RPA0323","Rhodopseudomonas palustris",6,"ARG A 120;LEU A 112;ALA A  28;VAL A  64;PRO A 123;ILE A 111","None","1.46A","3em6B-3fovA:undetectable","3em6B-3fovA:20.44"],["3UUD_A_ESTA600_1","ESTROGEN RECEPTOR","3fov","UPF0102 PROTEIN RPA0323","Rhodopseudomonas palustris",5,"LEU A  40;ALA A  62;LEU A  60;GLY A  36;LEU A  32","None","1.10A","3uudA-3fovA:undetectable","3uudA-3fovA:17.27"],["4DQF_B_017B101_1","ASPARTYL PROTEASE;ASPARTYL PROTEASE","3fov","UPF0102 PROTEIN RPA0323","Rhodopseudomonas palustris",6,"ARG A 120;LEU A 112;ALA A  28;VAL A  64;PRO A 123;ILE A 111","None","1.49A","4dqfA-3fovA:undetectable","4dqfA-3fovA:22.86"]]