SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fpn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A 221
ILE A 207
ILE A 213
ALA A 214
 None
 0.84A 2i30A-3fpnA:
2.1		 2i30A-3fpnA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 8 LEU B 176
VAL B 241
ILE B 221
PHE B 216
 None
 0.78A 2weyB-3fpnB:
undetectable		 2weyB-3fpnB:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 6 ASP A 189
ILE A 190
LEU A 192
GLU A 167
 None
 0.92A 2ya7A-3fpnA:
undetectable		 2ya7A-3fpnA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 6 ASP A 189
ILE A 190
LEU A 192
GLU A 167
 None
 0.90A 2ya7B-3fpnA:
undetectable		 2ya7B-3fpnA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 6 ASP A 189
ILE A 190
LEU A 192
GLU A 167
 None
 0.90A 2ya7D-3fpnA:
undetectable		 2ya7D-3fpnA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 6 GLU B 233
GLY B 232
LEU B 235
GLU B 201
 None
 1.12A 3w9tB-3fpnB:
undetectable		 3w9tB-3fpnB:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 6 GLU B 233
GLY B 232
LEU B 235
GLU B 201
 None
 1.13A 3w9tF-3fpnB:
undetectable		 3w9tF-3fpnB:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us) 		3 / 3 ARG A 170
ARG B 213
ASP B 228
 None
 0.67A 3wipG-3fpnA:
undetectable
3wipH-3fpnA:
undetectable		 3wipG-3fpnA:
18.61
3wipH-3fpnA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		4 / 6 GLU A 222
ASP B 185
ASN B 170
ARG B 169
 None
 1.24A 4ntxA-3fpnA:
undetectable
4ntxC-3fpnA:
undetectable		 4ntxA-3fpnA:
13.61
4ntxC-3fpnA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us;
Geobacillus
stearothermophil
us) 		4 / 6 LYS A 226
GLY A 173
GLU B 201
ASP B 228
 None
 1.25A 5emlA-3fpnA:
undetectable		 5emlA-3fpnA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		5 / 12 ASP B 198
GLU B 215
THR A 165
ARG A 176
LEU A 186
 None
 1.31A 5m50B-3fpnB:
undetectable		 5m50B-3fpnB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		5 / 12 VAL B 199
ASP B 198
GLU B 215
THR A 165
ARG A 176
 None
 1.14A 5m50B-3fpnB:
undetectable		 5m50B-3fpnB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		5 / 12 ASP B 198
GLU B 215
THR A 165
ARG A 176
LEU A 186
 None
 1.32A 5m50E-3fpnB:
undetectable		 5m50E-3fpnB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		5 / 12 VAL B 199
ASP B 198
GLU B 215
THR A 165
ARG A 176
 None
 1.13A 5m50E-3fpnB:
undetectable		 5m50E-3fpnB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		5 / 12 VAL B 199
ASP B 198
GLU B 215
THR A 165
LEU A 186
 None
 1.14A 5m54B-3fpnB:
undetectable		 5m54B-3fpnB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		5 / 12 VAL B 199
ASP B 198
THR A 165
ARG A 176
LEU A 186
 None
 1.31A 5m54B-3fpnB:
undetectable		 5m54B-3fpnB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		6 / 12 VAL B 199
ASP B 198
GLU B 215
THR A 165
ARG A 176
LEU A 186
 None
 1.33A 5m5cB-3fpnB:
undetectable		 5m5cB-3fpnB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN
GEOBACILLUS
STEAROTHERMOPHILUS
UVRB INTERACTION
DOMAIN
(Geobacillus
stearothermophil
us) 		5 / 10 VAL B 199
ASP B 198
GLU B 215
THR A 165
LEU A 186
 None
 1.24A 5m5cE-3fpnB:
undetectable		 5m5cE-3fpnB:
17.80