SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3fq4 INTEGRIN BETA-4
(Homo
sapiens) 		4 / 8 VAL A1001
GLY A1031
THR A1032
ALA A1033
 None
 0.88A 2a1hA-3fq4A:
undetectable
2a1hB-3fq4A:
undetectable		 2a1hA-3fq4A:
16.62
2a1hB-3fq4A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3fq4 INTEGRIN BETA-4
(Homo
sapiens) 		4 / 7 ASP A1030
VAL A1059
ILE A1010
TYR A1039
 None
 0.92A 3pglA-3fq4A:
undetectable		 3pglA-3fq4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 3fq4 INTEGRIN BETA-4
(Homo
sapiens) 		4 / 4 ILE A1102
VAL A1007
VAL A1001
ARG A1103
 None
 1.24A 4m6tA-3fq4A:
undetectable		 4m6tA-3fq4A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3fq4 INTEGRIN BETA-4
(Homo
sapiens) 		4 / 7 GLY A1051
LEU A1083
PHE A 994
ASP A 990
 None
 0.90A 5hieB-3fq4A:
undetectable		 5hieB-3fq4A:
21.03