SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 3fq6 METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ILE A 215
VAL A 218
VAL A 183
ARG A 185
 None
 1.18A 4m6tA-3fq6A:
undetectable		 4m6tA-3fq6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fq6 METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 199
SER A 198
GLY A 221
ALA A 220
LEU A 124
 None
 1.17A 4rrwA-3fq6A:
undetectable		 4rrwA-3fq6A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fq6 METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 199
SER A 198
GLY A 221
ALA A 220
LEU A 124
 None
 1.18A 4rrwB-3fq6A:
undetectable		 4rrwB-3fq6A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fq6 METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 199
SER A 198
GLY A 221
ALA A 220
LEU A 124
 None
 1.17A 4rrzA-3fq6A:
undetectable		 4rrzA-3fq6A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3fq6 METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 199
SER A 198
GLY A 221
ALA A 220
LEU A 124
 None
 1.18A 4rrzB-3fq6A:
undetectable		 4rrzB-3fq6A:
13.20