SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3frm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
4 / 8 TYR A 237
VAL A 218
ILE A 205
GLY A 210
None
0.96A 3n9jA-3frmA:
undetectable
3n9jA-3frmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
4 / 6 LEU A  27
SER A  36
TYR A  25
ALA A  35
None
1.04A 3ravA-3frmA:
undetectable
3ravA-3frmA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
3 / 3 ASP A 177
ARG A 163
ASP A  12
None
0.75A 4fp9D-3frmA:
undetectable
4fp9D-3frmA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
3 / 3 ASP A 177
ARG A 163
ASP A  12
None
0.77A 4fzvA-3frmA:
undetectable
4fzvA-3frmA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
3 / 3 ASN A  14
ASP A  12
ASP A 160
None
0.87A 4obwD-3frmA:
undetectable
4obwD-3frmA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
3 / 3 TYR A  10
ASP A 177
ASP A  12
None
0.78A 5x6yA-3frmA:
undetectable
5x6yA-3frmA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
3 / 3 ASP A 177
ARG A 163
ASP A  12
None
0.74A 5zvgA-3frmA:
undetectable
5zvgA-3frmA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis)
3 / 3 ASP A 177
ARG A 163
ASP A  12
None
0.72A 5zvgB-3frmA:
undetectable
5zvgB-3frmA:
24.10