SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3frn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		4 / 4 THR A 244
VAL A 278
GLY A 271
THR A 257
 None
 1.10A 3cflA-3frnA:
undetectable		 3cflA-3frnA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		3 / 3 ASN A 151
LEU A  56
PHE A 137
 None
 0.78A 4dajB-3frnA:
undetectable		 4dajB-3frnA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		5 / 12 LEU A  56
VAL A 148
VAL A 139
PRO A 119
TYR A  58
 None
 1.49A 4id5A-3frnA:
undetectable		 4id5A-3frnA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		5 / 12 LEU A  56
VAL A 148
VAL A 139
PRO A 119
TYR A  58
 None
 1.47A 4idkA-3frnA:
undetectable		 4idkA-3frnA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		5 / 12 LEU A  56
VAL A 148
VAL A 139
PRO A 119
TYR A  58
 None
 1.46A 4ifvA-3frnA:
undetectable		 4ifvA-3frnA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		5 / 12 LEU A  56
VAL A 148
VAL A 139
PRO A 119
TYR A  58
 None
 1.44A 4ifyA-3frnA:
undetectable		 4ifyA-3frnA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		5 / 12 LEU A  56
VAL A 148
VAL A 139
PRO A 119
TYR A  58
 None
 1.47A 4kfbA-3frnA:
undetectable		 4kfbA-3frnA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		5 / 12 ALA A 104
LEU A 154
ASN A 135
VAL A 129
LYS A 131
 None
 1.27A 4x1iB-3frnA:
undetectable		 4x1iB-3frnA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		4 / 8 ALA A  28
VAL A  84
PHE A 122
GLY A  31
 None
 0.92A 5v0vA-3frnA:
undetectable		 5v0vA-3frnA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		5 / 12 LEU A  56
VAL A 148
VAL A 139
PRO A 119
TYR A  58
 None
 1.47A 6eliA-3frnA:
undetectable		 6eliA-3frnA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 3frn FLAGELLAR PROTEIN
FLGA
(Thermotoga
maritima) 		3 / 3 LYS A 202
VAL A 219
ASP A 221
 None
 0.56A 6fgdA-3frnA:
undetectable		 6fgdA-3frnA:
22.58