SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3fru NEONATAL FC RECEPTOR
(Rattus
norvegicus) 		5 / 12 LEU A 242
GLU A 257
GLY A 222
SER A 223
LEU A 215
 None
 1.28A 3ou6D-3fruA:
undetectable		 3ou6D-3fruA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 3fru NEONATAL FC RECEPTOR
(Rattus
norvegicus) 		4 / 4 LEU A 166
GLY A 167
LEU A 169
GLU A 170
 None
 1.12A 3tgvB-3fruA:
undetectable		 3tgvB-3fruA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3fru BETA-2-MICROGLOBULIN
NEONATAL FC RECEPTOR
(Rattus
norvegicus) 		3 / 3 PRO A  22
LEU A  21
HIS B  31
 None
 0.72A 4pevA-3fruA:
undetectable		 4pevA-3fruA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 3fru BETA-2-MICROGLOBULIN
NEONATAL FC RECEPTOR
(Rattus
norvegicus) 		4 / 8 GLN A  93
LEU A  21
LEU B  54
THR A  27
 None
 0.96A 5hs6A-3fruA:
undetectable		 5hs6A-3fruA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3fru BETA-2-MICROGLOBULIN
NEONATAL FC RECEPTOR
(Rattus
norvegicus) 		4 / 5 GLY A 229
THR A 228
GLY B  43
LEU B  23
 None
 0.88A 5jlcA-3fruA:
undetectable		 5jlcA-3fruA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 3fru BETA-2-MICROGLOBULIN
NEONATAL FC RECEPTOR
(Rattus
norvegicus) 		4 / 6 THR A 228
GLY A 229
TYR B  63
ILE B  64
 None
 0.79A 5kmfA-3fruA:
undetectable
5kmfC-3fruA:
undetectable		 5kmfA-3fruA:
19.93
5kmfC-3fruA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3fru BETA-2-MICROGLOBULIN
NEONATAL FC RECEPTOR
(Rattus
norvegicus) 		4 / 5 THR A  19
THR A  91
HIS B  31
LEU B  54
 None
 1.42A 6aphA-3fruA:
undetectable		 6aphA-3fruA:
20.14