SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fs3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		4 / 5 PHE A 150
LEU A 107
PHE A 229
SER A 224
 None
 1.33A 1wrkB-3fs3A:
undetectable		 1wrkB-3fs3A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.34A 1xmuA-3fs3A:
undetectable		 1xmuA-3fs3A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_A_CIOA603_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.25A 1xomA-3fs3A:
undetectable		 1xomA-3fs3A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.25A 1xoqA-3fs3A:
undetectable		 1xoqA-3fs3A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.26A 1xoqB-3fs3A:
undetectable		 1xoqB-3fs3A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA A 185
PHE A 150
LEU A 107
TYR A 167
THR A 186
 None
 1.25A 2oipB-3fs3A:
undetectable		 2oipB-3fs3A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA A 185
PHE A 150
LEU A 107
TYR A 167
THR A 186
 None
 1.18A 2oipC-3fs3A:
undetectable		 2oipC-3fs3A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA A 185
PHE A 150
LEU A 107
TYR A 167
THR A 186
 None
 1.21A 3hj3A-3fs3A:
undetectable		 3hj3A-3fs3A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA A 185
PHE A 150
LEU A 107
TYR A 167
THR A 186
 None
 1.17A 3hj3C-3fs3A:
undetectable		 3hj3C-3fs3A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		4 / 7 PHE A 157
TYR A 127
ILE A  94
PRO A 156
 None
 1.03A 4g5jA-3fs3A:
undetectable		 4g5jA-3fs3A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 ASP A  80
ARG A 132
ASP A  73
 None
 0.88A 5zvgA-3fs3A:
undetectable		 5zvgA-3fs3A:
22.74