SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fs4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3fs4 HEMOGLOBIN SUBUNIT
BETA
(Struthio
camelus) 		4 / 7 PHE B  42
PHE B  45
VAL B  67
HIS B  92
 HEM  B 150 (-4.0A)
None
HEM  B 150 (-4.0A)
HEM  B 150 (-3.3A)
 0.82A 1lh6A-3fs4B:
14.0		 1lh6A-3fs4B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 3fs4 HEMOGLOBIN SUBUNIT
BETA
(Struthio
camelus) 		4 / 7 ASP B  79
SER B   4
LYS B   8
GLU B   6
 None
 0.96A 3bc9A-3fs4B:
undetectable		 3bc9A-3fs4B:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 3fs4 HEMOGLOBIN SUBUNIT
BETA
(Struthio
camelus) 		5 / 9 LEU B 106
GLY B 107
LEU B 110
LEU B  68
ALA B  27
 HEM  B 150 (-4.5A)
None
None
None
None
 1.10A 5dqfA-3fs4B:
1.8		 5dqfA-3fs4B:
13.62