SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fs5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3fs5 UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 138
LYS A  49
HIS A  25
 None
 0.94A 3elzA-3fs5A:
undetectable		 3elzA-3fs5A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3fs5 UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 4 LEU A  17
PRO A  14
LEU A 121
ARG A  39
 None
 1.32A 3hcoA-3fs5A:
3.2		 3hcoA-3fs5A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3fs5 UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  53
GLY A  97
ALA A 100
SER A  99
LEU A 103
 None
CME  A  90 ( 3.8A)
None
None
None
 1.26A 3n8xA-3fs5A:
undetectable		 3n8xA-3fs5A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3fs5 UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  48
LEU A  17
PHE A  33
GLY A  24
 None
 1.04A 3selX-3fs5A:
undetectable		 3selX-3fs5A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3fs5 UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  48
LEU A  17
PHE A  33
GLY A  24
 None
 0.97A 3sj1X-3fs5A:
undetectable		 3sj1X-3fs5A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3fs5 UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  48
LEU A  17
PHE A  33
GLY A  24
 None
 1.06A 4hbfA-3fs5A:
undetectable		 4hbfA-3fs5A:
14.47